Tracing human genetic histories and natural selection with precise local ancestry inference

Tracing human genetic histories and natural selection with precise local ancestry inference

Abstract Local ancestry inference is crucial for unraveling demographic histories, discovering selection signals, and including admixed individuals in genomic studies for improved equity and portability. To date, the precision and resolution of local ancestry inference were limited by technical and...

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Main Authors: Jon Lerga-Jaso, Biljana Novković, Deepu Unnikrishnan, Varuna Bamunusinghe, Marcelinus R. Hatorangan, Charlie Manson, Haley Pedersen, Alex Osama, Andrew Terpolovsky, Sandra Bohn, Adriano De Marino, Abdallah A. Mahmoud, Karatuğ O. Bircan, Umar Khan, Manfred G. Grabherr, Puya G. Yazdi
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-59936-3
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