Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue
We present the case of a woman with a history of autoimmune hemolytic anemia (AIHA), untreated for 1 year, who presented with fever, myalgia, arthralgia, anemia, and thrombocytopenia, along with a positive nonstructural protein antigen 1 (NS1Ag) test. During the course of dengue, the patient develop...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/carm/8165658 |
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| _version_ | 1849765110132768768 |
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| author | Christian Alberto Rodriguez-Saldaña Sofía Cavalcanti-Ramírez Carmen Claudia Quesada-Osoria Luis Gabriel Farfan-Chavez Guiovanna María Wong-Terrones Helena Karin Dominguez-Troncos |
| author_facet | Christian Alberto Rodriguez-Saldaña Sofía Cavalcanti-Ramírez Carmen Claudia Quesada-Osoria Luis Gabriel Farfan-Chavez Guiovanna María Wong-Terrones Helena Karin Dominguez-Troncos |
| author_sort | Christian Alberto Rodriguez-Saldaña |
| collection | DOAJ |
| description | We present the case of a woman with a history of autoimmune hemolytic anemia (AIHA), untreated for 1 year, who presented with fever, myalgia, arthralgia, anemia, and thrombocytopenia, along with a positive nonstructural protein antigen 1 (NS1Ag) test. During the course of dengue, the patient developed severe hemolytic anemia, posing a potentially life-threatening scenario due to the rapid decline in hemoglobin levels and the risk of multiorgan failure. Treatment with methylprednisolone was initiated alongside supportive care for dengue, and balancing corticosteroid risks in a viral infection was crucial to stabilize the patient, ultimately leading to a favorable outcome. This case highlights the importance of prompt diagnosis and integrated management of autoimmune diseases and viral coinfections in dengue-endemic areas. |
| format | Article |
| id | doaj-art-4d5032f5ede44b6581583701a25ff23e |
| institution | DOAJ |
| issn | 1687-9635 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-4d5032f5ede44b6581583701a25ff23e2025-08-20T03:04:58ZengWileyCase Reports in Medicine1687-96352025-01-01202510.1155/carm/8165658Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by DengueChristian Alberto Rodriguez-Saldaña0Sofía Cavalcanti-Ramírez1Carmen Claudia Quesada-Osoria2Luis Gabriel Farfan-Chavez3Guiovanna María Wong-Terrones4Helena Karin Dominguez-Troncos5José Cayetano Heredia Hospital III-1 EsSaludDepartment of Infectious DiseasesDepartment of Infectious DiseasesDepartment of PulmonologyDepartment of Internal MedicineDepartment of Internal MedicineWe present the case of a woman with a history of autoimmune hemolytic anemia (AIHA), untreated for 1 year, who presented with fever, myalgia, arthralgia, anemia, and thrombocytopenia, along with a positive nonstructural protein antigen 1 (NS1Ag) test. During the course of dengue, the patient developed severe hemolytic anemia, posing a potentially life-threatening scenario due to the rapid decline in hemoglobin levels and the risk of multiorgan failure. Treatment with methylprednisolone was initiated alongside supportive care for dengue, and balancing corticosteroid risks in a viral infection was crucial to stabilize the patient, ultimately leading to a favorable outcome. This case highlights the importance of prompt diagnosis and integrated management of autoimmune diseases and viral coinfections in dengue-endemic areas.http://dx.doi.org/10.1155/carm/8165658 |
| spellingShingle | Christian Alberto Rodriguez-Saldaña Sofía Cavalcanti-Ramírez Carmen Claudia Quesada-Osoria Luis Gabriel Farfan-Chavez Guiovanna María Wong-Terrones Helena Karin Dominguez-Troncos Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue Case Reports in Medicine |
| title | Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue |
| title_full | Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue |
| title_fullStr | Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue |
| title_full_unstemmed | Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue |
| title_short | Severe Hemolytic Crisis in Uncontrolled AIHA Triggered by Dengue |
| title_sort | severe hemolytic crisis in uncontrolled aiha triggered by dengue |
| url | http://dx.doi.org/10.1155/carm/8165658 |
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