Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography
Purpose. To investigate the effect of hemodialysis (HD) on the anterior chamber angle by anterior segment optical coherence tomography (ASOCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Methods. A prospective observational study was performed on 20 patients...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2019/2406547 |
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| author | Yong Un Shin Ji Hong Kim Heeyoon Cho Dae Sung Kim Joo-Hark Yi Sang-Woong Han Mincheol Seong |
| author_facet | Yong Un Shin Ji Hong Kim Heeyoon Cho Dae Sung Kim Joo-Hark Yi Sang-Woong Han Mincheol Seong |
| author_sort | Yong Un Shin |
| collection | DOAJ |
| description | Purpose. To investigate the effect of hemodialysis (HD) on the anterior chamber angle by anterior segment optical coherence tomography (ASOCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Methods. A prospective observational study was performed on 20 patients who underwent HD for ESKD. Anterior chamber angle images were obtained by 16 mm line scan of ASOCT. The angle opening distance (AOD) and the trabecular-iris space area (TISA) were determined using the ImageJ program. Additional 12 mm horizontal and 9 mm vertical wide-field scans centered on the posterior pole were performed for the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGCIPL) thickness. Changes in intraocular pressure (IOP), AOD, TISA, pRNFL thickness, and mGCIPL thickness before and after HD were statistically analyzed. Results. The IOP decreased significantly from 17.5 ± 3.4 before HD to 16.2 ± 2.3 after HD (P=0.017). There was a statistically significant decrease in AOD 750 and TISA 750 (P=0.005 and P=0.007, respectively). AOD 500 and TISA 500 also decreased, which was almost statistically significant (P=0.061 and P=0.081, respectively). Mean pRNFL thickness and mGCIPL thickness did not show significant change after HD. Conclusion. We observed a significant decrease in IOP and anterior chamber angle measurements after HD. Our study suggests that HD can influence the anterior segment structure of eyes. |
| format | Article |
| id | doaj-art-4d3efc27a48547de8dfbb011b5d4331c |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-4d3efc27a48547de8dfbb011b5d4331c2025-08-20T03:34:18ZengWileyJournal of Ophthalmology2090-004X2090-00582019-01-01201910.1155/2019/24065472406547Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence TomographyYong Un Shin0Ji Hong Kim1Heeyoon Cho2Dae Sung Kim3Joo-Hark Yi4Sang-Woong Han5Mincheol Seong6Department of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of KoreaDivision of Nephrology, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Republic of KoreaDivision of Nephrology, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Republic of KoreaDepartment of Ophthalmology, Hanyang University College of Medicine, Seoul, Republic of KoreaPurpose. To investigate the effect of hemodialysis (HD) on the anterior chamber angle by anterior segment optical coherence tomography (ASOCT) and other ophthalmologic parameters in patients with end-stage kidney disease (ESKD). Methods. A prospective observational study was performed on 20 patients who underwent HD for ESKD. Anterior chamber angle images were obtained by 16 mm line scan of ASOCT. The angle opening distance (AOD) and the trabecular-iris space area (TISA) were determined using the ImageJ program. Additional 12 mm horizontal and 9 mm vertical wide-field scans centered on the posterior pole were performed for the measurement of peripapillary retinal nerve fiber layer (pRNFL) thickness and macular ganglion cell-inner plexiform layer (mGCIPL) thickness. Changes in intraocular pressure (IOP), AOD, TISA, pRNFL thickness, and mGCIPL thickness before and after HD were statistically analyzed. Results. The IOP decreased significantly from 17.5 ± 3.4 before HD to 16.2 ± 2.3 after HD (P=0.017). There was a statistically significant decrease in AOD 750 and TISA 750 (P=0.005 and P=0.007, respectively). AOD 500 and TISA 500 also decreased, which was almost statistically significant (P=0.061 and P=0.081, respectively). Mean pRNFL thickness and mGCIPL thickness did not show significant change after HD. Conclusion. We observed a significant decrease in IOP and anterior chamber angle measurements after HD. Our study suggests that HD can influence the anterior segment structure of eyes.http://dx.doi.org/10.1155/2019/2406547 |
| spellingShingle | Yong Un Shin Ji Hong Kim Heeyoon Cho Dae Sung Kim Joo-Hark Yi Sang-Woong Han Mincheol Seong Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography Journal of Ophthalmology |
| title | Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography |
| title_full | Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography |
| title_fullStr | Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography |
| title_full_unstemmed | Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography |
| title_short | Effect of Hemodialysis on Anterior Chamber Angle Measured by Anterior Segment Optical Coherence Tomography |
| title_sort | effect of hemodialysis on anterior chamber angle measured by anterior segment optical coherence tomography |
| url | http://dx.doi.org/10.1155/2019/2406547 |
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