Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?

Introduction. Lymphoepithelioma-like carcinoma (LELC) of the salivary gland is a rare tumor. Currently, surgery with or without radiotherapy is the recommended treatment for all salivary gland carcinomas. However, in contrast to other high-grade salivary gland carcinomas, LELCs are considered radios...

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Main Authors: Orit Kaidar-Person, Abraham Kuten, Salem Billan
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Otolaryngology
Online Access:http://dx.doi.org/10.1155/2011/618650
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author Orit Kaidar-Person
Abraham Kuten
Salem Billan
author_facet Orit Kaidar-Person
Abraham Kuten
Salem Billan
author_sort Orit Kaidar-Person
collection DOAJ
description Introduction. Lymphoepithelioma-like carcinoma (LELC) of the salivary gland is a rare tumor. Currently, surgery with or without radiotherapy is the recommended treatment for all salivary gland carcinomas. However, in contrast to other high-grade salivary gland carcinomas, LELCs are considered radiosensitive. There are only a few published reports of radiotherapy alone for the treatment of salivary gland LELC. Case. We present two cases of LELC of the salivary gland. One was treated with surgery and postoperative radiotherapy, and the other was given a single cycle of chemotherapy and then radiotherapy. Currently, both patients have no evidence of disease. Conclusion. Radiotherapy as a single modality should be reevaluated. The role of systemic chemotherapy to gain systemic control should be addressed due to noteworthy metastatic disease.
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series Case Reports in Otolaryngology
spelling doaj-art-4d3c8a86804a4d9996e82c6066e32f472025-08-20T02:38:38ZengWileyCase Reports in Otolaryngology2090-67652090-67732011-01-01201110.1155/2011/618650618650Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?Orit Kaidar-Person0Abraham Kuten1Salem Billan2Division of Oncology, Rambam Health Care Campus, P.O. Box 9602, Haifa 31096, IsraelDivision of Oncology, Rambam Health Care Campus, P.O. Box 9602, Haifa 31096, IsraelDivision of Oncology, Rambam Health Care Campus, P.O. Box 9602, Haifa 31096, IsraelIntroduction. Lymphoepithelioma-like carcinoma (LELC) of the salivary gland is a rare tumor. Currently, surgery with or without radiotherapy is the recommended treatment for all salivary gland carcinomas. However, in contrast to other high-grade salivary gland carcinomas, LELCs are considered radiosensitive. There are only a few published reports of radiotherapy alone for the treatment of salivary gland LELC. Case. We present two cases of LELC of the salivary gland. One was treated with surgery and postoperative radiotherapy, and the other was given a single cycle of chemotherapy and then radiotherapy. Currently, both patients have no evidence of disease. Conclusion. Radiotherapy as a single modality should be reevaluated. The role of systemic chemotherapy to gain systemic control should be addressed due to noteworthy metastatic disease.http://dx.doi.org/10.1155/2011/618650
spellingShingle Orit Kaidar-Person
Abraham Kuten
Salem Billan
Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?
Case Reports in Otolaryngology
title Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?
title_full Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?
title_fullStr Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?
title_full_unstemmed Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?
title_short Lymphoepithelioma-Like Carcinoma of the Salivary Gland: Is Radiotherapy Alone Adequate?
title_sort lymphoepithelioma like carcinoma of the salivary gland is radiotherapy alone adequate
url http://dx.doi.org/10.1155/2011/618650
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AT salembillan lymphoepitheliomalikecarcinomaofthesalivaryglandisradiotherapyaloneadequate