Behavioral inflexibility through overtraining is mediated by reduced mGluR1/5 signaling capacity in the dorsolateral striatum.
The control of instrumental actions engages distinct behavioral strategies whose contributions are regulated with experience. Instrumental performance, which depends on the causal relationship between actions and their outcomes (A-O), relies on flexible, goal-directed control of behavior. Actions ca...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-07-01
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| Series: | PLoS Biology |
| Online Access: | https://doi.org/10.1371/journal.pbio.3003288 |
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