Synthesis and Evaluation of a Chitosan-Based Cationic Hydrogel with Strong Antifungal and Antibiofilm Activities Against Clinical Isolates of <i>Candida auris</i>

Synthesis and Evaluation of a Chitosan-Based Cationic Hydrogel with Strong Antifungal and Antibiofilm Activities Against Clinical Isolates of <i>Candida auris</i>

<b>Background: </b><i>Candida auris</i> is a significant global health concern, due to its rapid transmission, high mortality rate, and resistance to commonly available antifungal drugs. <b>Methodology:</b> During the current study, a cationic polymeric hydrogel w...

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Main Authors: Muhammad Kamran, Maryam Aftab, Afreenish Amir, Fatima Javed, Amtul Quddos Latif, Kausar Abbas Saldera, Abdul Ahad, Yousef A. Bin Jardan, Louise Ann Walker, Kiran Nisa, Faheem Ullah, Naseer Ali Shah
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Pharmaceuticals
Subjects:
<i>Candida auris</i>
antimicrobial resistance
antifungal activity
biofilm
candidemia
chitosan
Online Access:https://www.mdpi.com/1424-8247/18/4/506
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