The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections
Background: Maternal influenza vaccination is a vital public health strategy that safeguards both pregnant women and their newborns against severe respiratory infections. Influenza during pregnancy increases the risk of complications, including hospitalization and adverse neonatal outcomes. This rev...
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| Format: | Article |
| Language: | English |
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Zagazig University, Faculty of Medicine
2025-08-01
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| Series: | Microbes and Infectious Diseases |
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| Online Access: | https://mid.journals.ekb.eg/article_418386_aa3e348b7aeeac4540ff137963c9b598.pdf |
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| author | Fartun Mohamed ZamZam Mohammed Abdirasak Ali Kizito Bello Yahye Nageye |
| author_facet | Fartun Mohamed ZamZam Mohammed Abdirasak Ali Kizito Bello Yahye Nageye |
| author_sort | Fartun Mohamed |
| collection | DOAJ |
| description | Background: Maternal influenza vaccination is a vital public health strategy that safeguards both pregnant women and their newborns against severe respiratory infections. Influenza during pregnancy increases the risk of complications, including hospitalization and adverse neonatal outcomes. This review evaluates the effectiveness of maternal influenza immunization in reducing neonatal respiratory infections by enhancing passive immunity. It examines the mechanisms of transplacental antibody transfer, which provide early-life protection for infants who are highly susceptible to severe influenza-related complications. Evidence from clinical trials and large-scale vaccination programs demonstrates significant reductions in influenza-related morbidity among neonates born to vaccinated mothers. Despite these benefits, maternal influenza vaccine uptake remains suboptimal due to concerns about vaccine safety, limited awareness, and healthcare access barriers. Addressing these challenges requires targeted public health interventions, including educational campaigns, healthcare provider recommendations, and policy initiatives aimed at increasing accessibility and acceptance of maternal immunization. Strengthening global efforts to improve maternal vaccination coverage can substantially reduce the burden of neonatal respiratory infections, decrease healthcare costs, and enhance overall maternal and infant health outcomes. By reviewing current evidence and identifying strategies for improvement, this paper underscores the critical role of maternal influenza vaccination in protecting the most vulnerable populations. |
| format | Article |
| id | doaj-art-4d1d6f73307b4996b468a0bfaae7dbb5 |
| institution | Kabale University |
| issn | 2682-4132 2682-4140 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Zagazig University, Faculty of Medicine |
| record_format | Article |
| series | Microbes and Infectious Diseases |
| spelling | doaj-art-4d1d6f73307b4996b468a0bfaae7dbb52025-08-20T03:59:16ZengZagazig University, Faculty of MedicineMicrobes and Infectious Diseases2682-41322682-41402025-08-01632023203310.21608/mid.2025.357627.2503418386The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infectionsFartun Mohamed0ZamZam Mohammed1Abdirasak Ali2Kizito Bello3Yahye Nageye4Maternity Department, Banadir Hospital, Mogadishu, SomaliaBlood Banking Unit, Banadir Hospital, Mogadishu, SomaliaBlood Banking Unit, Banadir Hospital, Mogadishu, SomaliaKogi State (Prince Abubakar Audu) University, AnyigbaFaculty of Medicine and Health Sciences, SIMAD University, Mogadishu, Somalia, 252Background: Maternal influenza vaccination is a vital public health strategy that safeguards both pregnant women and their newborns against severe respiratory infections. Influenza during pregnancy increases the risk of complications, including hospitalization and adverse neonatal outcomes. This review evaluates the effectiveness of maternal influenza immunization in reducing neonatal respiratory infections by enhancing passive immunity. It examines the mechanisms of transplacental antibody transfer, which provide early-life protection for infants who are highly susceptible to severe influenza-related complications. Evidence from clinical trials and large-scale vaccination programs demonstrates significant reductions in influenza-related morbidity among neonates born to vaccinated mothers. Despite these benefits, maternal influenza vaccine uptake remains suboptimal due to concerns about vaccine safety, limited awareness, and healthcare access barriers. Addressing these challenges requires targeted public health interventions, including educational campaigns, healthcare provider recommendations, and policy initiatives aimed at increasing accessibility and acceptance of maternal immunization. Strengthening global efforts to improve maternal vaccination coverage can substantially reduce the burden of neonatal respiratory infections, decrease healthcare costs, and enhance overall maternal and infant health outcomes. By reviewing current evidence and identifying strategies for improvement, this paper underscores the critical role of maternal influenza vaccination in protecting the most vulnerable populations.https://mid.journals.ekb.eg/article_418386_aa3e348b7aeeac4540ff137963c9b598.pdfinfluenzavaccinationrespiratory infectionneonates and effectiveness |
| spellingShingle | Fartun Mohamed ZamZam Mohammed Abdirasak Ali Kizito Bello Yahye Nageye The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections Microbes and Infectious Diseases influenza vaccination respiratory infection neonates and effectiveness |
| title | The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections |
| title_full | The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections |
| title_fullStr | The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections |
| title_full_unstemmed | The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections |
| title_short | The Effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections |
| title_sort | effectiveness of maternal influenza vaccination in protecting neonates from respiratory infections |
| topic | influenza vaccination respiratory infection neonates and effectiveness |
| url | https://mid.journals.ekb.eg/article_418386_aa3e348b7aeeac4540ff137963c9b598.pdf |
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