Opisthorchiasis and pancreatic cancer

Chronic opisthorchiasis is recognized as a precancerous condition that can present similarly to other diseases of the hepatopancreatoduodenal zone. Statistically, there is a proven correlation between the duration and intensity of parasitic invasion and the development of carcinogenesis, with the ma...

Full description

Saved in:
Bibliographic Details
Main Authors: V. V. Ivanov, T. B. Komkova, I. A. Lyzko, E. A. Perina, I. A. Popov, E. V. Udut, E. S. Khmelevskaya
Format: Article
Language:English
Published: Siberian State Medical University (Tomsk) 2025-04-01
Series:Бюллетень сибирской медицины
Subjects:
Online Access:https://bulletin.ssmu.ru/jour/article/view/5976
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849773265114890240
author V. V. Ivanov
T. B. Komkova
I. A. Lyzko
E. A. Perina
I. A. Popov
E. V. Udut
E. S. Khmelevskaya
author_facet V. V. Ivanov
T. B. Komkova
I. A. Lyzko
E. A. Perina
I. A. Popov
E. V. Udut
E. S. Khmelevskaya
author_sort V. V. Ivanov
collection DOAJ
description Chronic opisthorchiasis is recognized as a precancerous condition that can present similarly to other diseases of the hepatopancreatoduodenal zone. Statistically, there is a proven correlation between the duration and intensity of parasitic invasion and the development of carcinogenesis, with the manifestations of opisthorchiasis often obscuring the early symptoms of cancer. Many researchers are working to find methods for the early diagnosis of pancreatic cancer against the background of chronic opisthorchiasis, which may enable timely treatment of the disease in the early stages. The authors of this lecture present a literary review of the data on the incidence of pancreatic cancer in patients with chronic opisthorchiasis. Additionally, some factors contributing to cholangiocarcinoma carcinogenesis are discussed, since the exact mechanisms leading from the introduction of a trematode to the formation of a malignant process are multifunctional. Certain phenomena regarding the effect of opisthorchis on the human body currently lack explanation and require further study and clarification.
format Article
id doaj-art-4d18cc2c89624852857cfc5abd9a5c07
institution DOAJ
issn 1682-0363
1819-3684
language English
publishDate 2025-04-01
publisher Siberian State Medical University (Tomsk)
record_format Article
series Бюллетень сибирской медицины
spelling doaj-art-4d18cc2c89624852857cfc5abd9a5c072025-08-20T03:02:06ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842025-04-0124117317910.20538/1682-0363-2025-1-173-1793148Opisthorchiasis and pancreatic cancerV. V. Ivanov0T. B. Komkova1I. A. Lyzko2E. A. Perina3I. A. Popov4E. V. Udut5E. S. Khmelevskaya6Siberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversitySiberian State Medical UniversityMoscow Institute of Physics and TechnologySiberian State Medical UniversitySiberian State Medical UniversityChronic opisthorchiasis is recognized as a precancerous condition that can present similarly to other diseases of the hepatopancreatoduodenal zone. Statistically, there is a proven correlation between the duration and intensity of parasitic invasion and the development of carcinogenesis, with the manifestations of opisthorchiasis often obscuring the early symptoms of cancer. Many researchers are working to find methods for the early diagnosis of pancreatic cancer against the background of chronic opisthorchiasis, which may enable timely treatment of the disease in the early stages. The authors of this lecture present a literary review of the data on the incidence of pancreatic cancer in patients with chronic opisthorchiasis. Additionally, some factors contributing to cholangiocarcinoma carcinogenesis are discussed, since the exact mechanisms leading from the introduction of a trematode to the formation of a malignant process are multifunctional. Certain phenomena regarding the effect of opisthorchis on the human body currently lack explanation and require further study and clarification.https://bulletin.ssmu.ru/jour/article/view/5976cholangiocarcinomapancreatic cancercholangiogenic canceropisthorchiasis invasion
spellingShingle V. V. Ivanov
T. B. Komkova
I. A. Lyzko
E. A. Perina
I. A. Popov
E. V. Udut
E. S. Khmelevskaya
Opisthorchiasis and pancreatic cancer
Бюллетень сибирской медицины
cholangiocarcinoma
pancreatic cancer
cholangiogenic cancer
opisthorchiasis invasion
title Opisthorchiasis and pancreatic cancer
title_full Opisthorchiasis and pancreatic cancer
title_fullStr Opisthorchiasis and pancreatic cancer
title_full_unstemmed Opisthorchiasis and pancreatic cancer
title_short Opisthorchiasis and pancreatic cancer
title_sort opisthorchiasis and pancreatic cancer
topic cholangiocarcinoma
pancreatic cancer
cholangiogenic cancer
opisthorchiasis invasion
url https://bulletin.ssmu.ru/jour/article/view/5976
work_keys_str_mv AT vvivanov opisthorchiasisandpancreaticcancer
AT tbkomkova opisthorchiasisandpancreaticcancer
AT ialyzko opisthorchiasisandpancreaticcancer
AT eaperina opisthorchiasisandpancreaticcancer
AT iapopov opisthorchiasisandpancreaticcancer
AT evudut opisthorchiasisandpancreaticcancer
AT eskhmelevskaya opisthorchiasisandpancreaticcancer