Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment
Abstract INTRODUCTION This study examines the link between daytime and nighttime excessive sleep and cognition, cognitive decline, and dementia in individuals with existing mild cognitive impairment (MCI). METHODS Using data from the Swedish longitudinal study Good Aging in Skåne, participants aged...
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| Language: | English |
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Wiley
2025-01-01
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| Series: | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
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| Online Access: | https://doi.org/10.1002/dad2.70093 |
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| author | Marieclaire Overton Shireen Sindi Rani Basna Sölve Elmståhl |
| author_facet | Marieclaire Overton Shireen Sindi Rani Basna Sölve Elmståhl |
| author_sort | Marieclaire Overton |
| collection | DOAJ |
| description | Abstract INTRODUCTION This study examines the link between daytime and nighttime excessive sleep and cognition, cognitive decline, and dementia in individuals with existing mild cognitive impairment (MCI). METHODS Using data from the Swedish longitudinal study Good Aging in Skåne, participants aged 60–102 years were retrospectively classified as MCI based on cognitive testing. The average follow‐up time was 6.59 years. Mixed linear models assessed cross‐sectional and longitudinal associations between excessive sleep patterns (napping ≥2 h or nighttime sleep ≥9 h) and multiple cognitive domains. Cox regressions estimated dementia risk for excessive sleep. RESULTS Of 4930 participants, 2052 (41%) had MCI. Excessive daytime napping and nighttime sleep were associated with worse cognition and cognitive decline. Excessive napping and nighttime sleep were also linked to higher dementia risk (hazard ratios: 1.75 and 1.86, respectively). DISCUSSION These findings suggest that excessive sleep in MCI is associated with further cognitive decline and dementia. Highlights Excessive daytime napping and nighttime sleep are linked cognitive decline for those with MCI. Excessive sleep during the day or at night heighten dementia risk. Worse test scores across multiple cognitive domains were observed for excessive daytime nappers. Excessive sleep in MCI may be a warning sign for further cognitive decline. |
| format | Article |
| id | doaj-art-4d17dd1b64ce4a95827e8a364de25739 |
| institution | OA Journals |
| issn | 2352-8729 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring |
| spelling | doaj-art-4d17dd1b64ce4a95827e8a364de257392025-08-20T02:09:58ZengWileyAlzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring2352-87292025-01-01171n/an/a10.1002/dad2.70093Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairmentMarieclaire Overton0Shireen Sindi1Rani Basna2Sölve Elmståhl3Division of Geriatric Medicine Department of Clinical Sciences in Malmö Skåne University Hospital Lund University Malmö SwedenDivision of Clinical Geriatrics Center for Alzheimer Research Karolinska Institutet and Karolinska University Hospital Malmö SwedenDivision of Geriatric Medicine Department of Clinical Sciences in Malmö Skåne University Hospital Lund University Malmö SwedenDivision of Geriatric Medicine Department of Clinical Sciences in Malmö Skåne University Hospital Lund University Malmö SwedenAbstract INTRODUCTION This study examines the link between daytime and nighttime excessive sleep and cognition, cognitive decline, and dementia in individuals with existing mild cognitive impairment (MCI). METHODS Using data from the Swedish longitudinal study Good Aging in Skåne, participants aged 60–102 years were retrospectively classified as MCI based on cognitive testing. The average follow‐up time was 6.59 years. Mixed linear models assessed cross‐sectional and longitudinal associations between excessive sleep patterns (napping ≥2 h or nighttime sleep ≥9 h) and multiple cognitive domains. Cox regressions estimated dementia risk for excessive sleep. RESULTS Of 4930 participants, 2052 (41%) had MCI. Excessive daytime napping and nighttime sleep were associated with worse cognition and cognitive decline. Excessive napping and nighttime sleep were also linked to higher dementia risk (hazard ratios: 1.75 and 1.86, respectively). DISCUSSION These findings suggest that excessive sleep in MCI is associated with further cognitive decline and dementia. Highlights Excessive daytime napping and nighttime sleep are linked cognitive decline for those with MCI. Excessive sleep during the day or at night heighten dementia risk. Worse test scores across multiple cognitive domains were observed for excessive daytime nappers. Excessive sleep in MCI may be a warning sign for further cognitive decline.https://doi.org/10.1002/dad2.70093dementiaexcessive nappingexcessive sleeplong nighttime sleepmild cognitive impairmentsleep duration |
| spellingShingle | Marieclaire Overton Shireen Sindi Rani Basna Sölve Elmståhl Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring dementia excessive napping excessive sleep long nighttime sleep mild cognitive impairment sleep duration |
| title | Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment |
| title_full | Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment |
| title_fullStr | Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment |
| title_full_unstemmed | Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment |
| title_short | Excessive sleep is associated with worse cognition, cognitive decline, and dementia in mild cognitive impairment |
| title_sort | excessive sleep is associated with worse cognition cognitive decline and dementia in mild cognitive impairment |
| topic | dementia excessive napping excessive sleep long nighttime sleep mild cognitive impairment sleep duration |
| url | https://doi.org/10.1002/dad2.70093 |
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