Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis
Abstract Multiple sclerosis (MS) is a neuroimmunological disorder which causes axonal damage, demyelination and paralysis. Although numerous therapeutics have been developed for the effective treatment of MS and a few have been approved in recent decades, complete remission and treatment of MS remai...
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| Format: | Article |
| Language: | English |
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Springer
2024-10-01
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| Series: | Discover Nano |
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| Online Access: | https://doi.org/10.1186/s11671-024-04135-0 |
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| author | Archna Panghal S. J. S. Flora |
| author_facet | Archna Panghal S. J. S. Flora |
| author_sort | Archna Panghal |
| collection | DOAJ |
| description | Abstract Multiple sclerosis (MS) is a neuroimmunological disorder which causes axonal damage, demyelination and paralysis. Although numerous therapeutics have been developed for the effective treatment of MS and a few have been approved in recent decades, complete remission and treatment of MS remain a matter of concern. Nanotechnology is a potential approach for manipulating the properties of materials at the molecular level to attain desired properties. This approach is effective in the treatment of several CNS disorders by enhancing drug delivery, bioavailability and efficacy. We have briefly discussed the neuroimmunological disorders with a particular emphasis on MS. We also explored nanoengineered drug delivery systems, describing several nano-formulations for the treatment of MS, challenges and future of nanotechnology. |
| format | Article |
| id | doaj-art-4d105084380f4d969637144abc5c7c21 |
| institution | OA Journals |
| issn | 2731-9229 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Springer |
| record_format | Article |
| series | Discover Nano |
| spelling | doaj-art-4d105084380f4d969637144abc5c7c212025-08-20T02:18:28ZengSpringerDiscover Nano2731-92292024-10-0119112010.1186/s11671-024-04135-0Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosisArchna Panghal0S. J. S. Flora1Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research-SAS NagarDepartment of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research-SAS NagarAbstract Multiple sclerosis (MS) is a neuroimmunological disorder which causes axonal damage, demyelination and paralysis. Although numerous therapeutics have been developed for the effective treatment of MS and a few have been approved in recent decades, complete remission and treatment of MS remain a matter of concern. Nanotechnology is a potential approach for manipulating the properties of materials at the molecular level to attain desired properties. This approach is effective in the treatment of several CNS disorders by enhancing drug delivery, bioavailability and efficacy. We have briefly discussed the neuroimmunological disorders with a particular emphasis on MS. We also explored nanoengineered drug delivery systems, describing several nano-formulations for the treatment of MS, challenges and future of nanotechnology.https://doi.org/10.1186/s11671-024-04135-0NanotechnologyNeuro-immunological disordersMultiple sclerosisNanoparticlesLiposomesDendrimers |
| spellingShingle | Archna Panghal S. J. S. Flora Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis Discover Nano Nanotechnology Neuro-immunological disorders Multiple sclerosis Nanoparticles Liposomes Dendrimers |
| title | Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis |
| title_full | Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis |
| title_fullStr | Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis |
| title_full_unstemmed | Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis |
| title_short | Nano-based approaches for the treatment of neuro-immunological disorders: a special emphasis on multiple sclerosis |
| title_sort | nano based approaches for the treatment of neuro immunological disorders a special emphasis on multiple sclerosis |
| topic | Nanotechnology Neuro-immunological disorders Multiple sclerosis Nanoparticles Liposomes Dendrimers |
| url | https://doi.org/10.1186/s11671-024-04135-0 |
| work_keys_str_mv | AT archnapanghal nanobasedapproachesforthetreatmentofneuroimmunologicaldisordersaspecialemphasisonmultiplesclerosis AT sjsflora nanobasedapproachesforthetreatmentofneuroimmunologicaldisordersaspecialemphasisonmultiplesclerosis |