Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma
T helper 17 () is a novel subset of T helper cells that has recently been identified in the hepatocellular carcinoma (HCC) tumor environment. Its presence seems to be linked with HCC progression, possibly via facilitating angiogenesis. The origin of tumor-associated may be related to the gut, in wh...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
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| Series: | International Journal of Hepatology |
| Online Access: | http://dx.doi.org/10.1155/2012/439024 |
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| _version_ | 1832555857843322880 |
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| author | Cecilia Ying Ju Sung Nikki Pui-yue Lee Hani El-Nezami |
| author_facet | Cecilia Ying Ju Sung Nikki Pui-yue Lee Hani El-Nezami |
| author_sort | Cecilia Ying Ju Sung |
| collection | DOAJ |
| description | T helper 17 () is a novel subset of T helper cells that has recently been identified in the hepatocellular carcinoma (HCC) tumor environment. Its presence seems to be linked with HCC progression, possibly via facilitating angiogenesis. The origin of tumor-associated may be related to the gut, in which the differentiation of T cells, especially cells, is affected by microbiota. As may appear to be a new therapeutic target against tumor-promoting inflammation, strategies such as using probiotics to polarize the response away from may be beneficial to slow down tumor progression. This paper will attempt to discuss the potential linkage between HCC progression, , and gut microbiota and the possible therapeutic implications of probiotics to modulate -mediated response for tumor growth. |
| format | Article |
| id | doaj-art-4d0d69c2fada444092f71e7d06faa98c |
| institution | Kabale University |
| issn | 2090-3448 2090-3456 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hepatology |
| spelling | doaj-art-4d0d69c2fada444092f71e7d06faa98c2025-02-03T05:46:57ZengWileyInternational Journal of Hepatology2090-34482090-34562012-01-01201210.1155/2012/439024439024Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular CarcinomaCecilia Ying Ju Sung0Nikki Pui-yue Lee1Hani El-Nezami2School of Biological Sciences, Faculty of Sciences, Kadoorie Biological Sciences Building, The University of Hong Kong, Pokfulam, Hong KongDepartment of Surgery, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong KongSchool of Biological Sciences, Faculty of Sciences, Kadoorie Biological Sciences Building, The University of Hong Kong, Pokfulam, Hong KongT helper 17 () is a novel subset of T helper cells that has recently been identified in the hepatocellular carcinoma (HCC) tumor environment. Its presence seems to be linked with HCC progression, possibly via facilitating angiogenesis. The origin of tumor-associated may be related to the gut, in which the differentiation of T cells, especially cells, is affected by microbiota. As may appear to be a new therapeutic target against tumor-promoting inflammation, strategies such as using probiotics to polarize the response away from may be beneficial to slow down tumor progression. This paper will attempt to discuss the potential linkage between HCC progression, , and gut microbiota and the possible therapeutic implications of probiotics to modulate -mediated response for tumor growth.http://dx.doi.org/10.1155/2012/439024 |
| spellingShingle | Cecilia Ying Ju Sung Nikki Pui-yue Lee Hani El-Nezami Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma International Journal of Hepatology |
| title | Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma |
| title_full | Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma |
| title_fullStr | Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma |
| title_full_unstemmed | Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma |
| title_short | Regulation of T Helper 17 by Bacteria: An Approach for the Treatment of Hepatocellular Carcinoma |
| title_sort | regulation of t helper 17 by bacteria an approach for the treatment of hepatocellular carcinoma |
| url | http://dx.doi.org/10.1155/2012/439024 |
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