Predicting ROS1 and ALK fusions in NSCLC from H&E slides with a two-step vision transformer approach
Abstract Non-small cell lung cancer (NSCLC) is one of the deadliest and most prevalent cancers worldwide, with 5-year survival rates of ~28%. The molecular heterogeneity within NSCLC encompasses several types of genetic alterations, such as mutations, amplifications, and rearrangements, and can driv...
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| Main Authors: | Eghbal Amidi, Mohammadreza Ramzanpour, Ming Chen, Tommy Boucher, Mukund Varma, Timothy Samec, Brian Lamon, Nicolas Stransky, Mark R. Miglarese, Matthew Oberley, David Spetzler, George W. Sledge |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | npj Precision Oncology |
| Online Access: | https://doi.org/10.1038/s41698-025-01037-x |
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