Discovery of Carbonic Anhydrase 9 as a Novel CLEC2 Ligand in a Cellular Interactome Screen

Discovery of Carbonic Anhydrase 9 as a Novel CLEC2 Ligand in a Cellular Interactome Screen

Membrane proteins, especially extracellular domains, are key therapeutic targets due to their role in cell communication and associations. Yet, their functions and interactions often remain unclear. This study presents a general method to discover interactions of membrane proteins with immune cells...

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Bibliographic Details
Main Authors:	Sebastian Hoffmann, Benedict-Tilman Berger, Liane Rosalie Lucas, Felix Schiele, John Edward Park
Format:	Article
Language:	English
Published:	MDPI AG 2024-12-01
Series:	Cells
Subjects:	carbonic anhydrase 9 (CA9 CAH9 CAIX) C-type lectin-like receptor 2 (CLEC2) podoplanin (PDPN) recombinant membrane protein library
Online Access:	https://www.mdpi.com/2073-4409/13/24/2083
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