Respiratory syncytial virus fuses with plasma membrane to infect primary cultures of bronchial epithelial cells

Respiratory syncytial virus fuses with plasma membrane to infect primary cultures of bronchial epithelial cells

BackgroundRespiratory syncytial virus (RSV) is a common cause of bronchiolitis in children under the age of five. RSV infection proceeds by fusion of the viral envelope with the target cell membrane, but it is unclear whether fusion occurs with plasma or endosomal membranes.MethodsEntry and/or infec...

Full description

Saved in:

Bibliographic Details
Main Authors:	Christian Cadena-Cruz, Marcio De-Avila-Arias, Heather M. Costello, Leidy Hurtado-Gomez, Walter Martínez-De-La-Rosa, Gigliola Macchia-Ceballos, Wendy Rosales-Rada, Gerardo Valencia-Villa, Pedro Villalba-Amarís, Meisam Naeimi Kararoudi, Mark E. Peeples, Homero San-Juan-Vergara
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-02-01
Series:	Frontiers in Microbiology
Subjects:	respiratory sycytial virus synchronization plasma membrane viral entry endocytosis
Online Access:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1498955/full
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Inhibition of early EHDV2-Ibaraki infection steps in bovine cells by endosome alkalinization or ikarugamycin, but not by blockage of individual endocytic pathways
by: Maya Malka, et al.
Published: (2025-02-01)

The larger attachment glycoprotein of respiratory syncytial virus produced in primary human bronchial epithelial cultures reduces infectivity for cell lines.
by: Tiffany King, et al.
Published: (2021-04-01)

Deltacoronavirus HKU11, HKU13, PDCoV (HKU15) and HKU17 spike pseudoviruses enter avian DF-1 cells via clathrin-mediated endocytosis in a Rab5-, Rab7- and pH-dependent manner
by: Qi-Zhang Liang, et al.
Published: (2025-01-01)

Endophilin-A2-mediated endocytic pathway is critical for enterovirus 71 entry into caco-2 cells
by: Sheng-Lin Chen, et al.
Published: (2019-01-01)

The Virus Entry Pathway Determines Sensitivity to the Antiviral Peptide TAT-I24
by: Eva Kicker, et al.
Published: (2025-03-01)

Diphyllin elicits a doubled-pronged attack on the entry of SARS-CoV-2 by inhibiting cathepsin L and furin
by: Binli Mao, et al.
Published: (2024-12-01)

CD1d facilitates African swine fever virus entry into the host cells via clathrin-mediated endocytosis
by: Xin Chen, et al.
Published: (2023-12-01)

From Structure to Function: The Promise of PAMAM Dendrimers in Biomedical Applications
by: Said Alamos-Musre, et al.
Published: (2025-07-01)

Boundary Flow-Induced Membrane Tubulation Under Turgor Pressures
by: Hao Xue, et al.
Published: (2025-04-01)

Isoflurane induces Art2‐Rsp5‐dependent endocytosis of Bap2 in yeast
by: Fumi Kozu, et al.
Published: (2021-11-01)

On the Complex Flow Dynamics of Shear Thickening Fluids Entry Flows
by: Miguel Montenegro, et al.
Published: (2024-10-01)

Advances in development of antiviral strategies against respiratory syncytial virus
by: Ge Yang, et al.
Published: (2025-04-01)

Impact of microplastics and nanoplastics on human Health: Emerging evidence and future directions
by: Sona Alungal Sadique, et al.
Published: (2025-09-01)

Research progresses on functional roles and regulation mechanisms of nutrient element transporters in plants
by: CHEN Di, et al.
Published: (2018-05-01)

The protein architecture of the endocytic coat analyzed by FRET microscopy
by: Michal Skruzny, et al.
Published: (2020-05-01)

Endocytosis of the IFNAR1 chain of Type 1 interferon receptor is regulated by diverse E2 ubiquitin conjugation enzymes
by: Christopher J. Carbone, et al.
Published: (2015-06-01)

Induced mitochondrial deficit by NDUFS3 transient silencing reduces RAB7 expression and causes lysosomal dysfunction in pancreatic cancer cells
by: Giulia Girolimetti, et al.
Published: (2025-05-01)

Endocytosis of the IFNAR1 chain of Type 1 interferon receptor is regulated by diverse E2 ubiquitin conjugation enzymes
Published: (2015-06-01)

Inhibition of osteoclast differentiation by (1→3)-β-D-glucan from Alcaligenes faecalis (curdlan) and dectin-1 interaction via the syk proteolytic system
by: Wataru Ariyoshi, et al.
Published: (2025-03-01)

Corrigendum: Subgrid channel formulation in an integrated surface-subsurface hydrologic model
by: Amelia Peeples, et al.
Published: (2025-05-01)

Subgrid channel formulation in an integrated surface-subsurface hydrologic model
by: Amelia Peeples, et al.
Published: (2025-01-01)

Regulation of Notch signaling by multiple Ankyrin repeat containing protein Mask
by: Bappi Sarkar, et al.
Published: (2025-07-01)

Strategies and scheming: the war between PRRSV and host cells
by: Fan Gao, et al.
Published: (2025-06-01)

Nobiletin Regulates Lysosome Function in Bovine Endometrial Epithelial Cells
by: Karen Koshimizu, et al.
Published: (2024-11-01)

Lack of phosphatidylinositol 3-kinase VPS34 in regulatory T cells leads to a fatal lymphoproliferative disorder without affecting their development
by: Christina J. F. Courreges, et al.
Published: (2024-11-01)

Revisiting the role of Annexins in membrane trafficking
by: Thomas Grewal, et al.
Published: (2025-06-01)

Biosynthesized nanoparticles of Tibetan medicine mercuric sulfide preparation to promote endocytosis and realize drug crossing through blood brain barrier
by: Wenjing Jia, et al.
Published: (2025-06-01)

F.V. Yezerskiy Personality’s Influence on the Development of his Scientific Views
by: V. Ya. Sokolov, et al.
Published: (2025-02-01)

Histodynamics of Natural Killer Cells from a Healthy Donor Exposed to Exosomes from the Blood of Hepatocellular Carcinoma Patients
by: Indria Asrinda, et al.
Published: (2024-12-01)

Modelling Lowe syndrome and Dent-2 disease using zebrafish
by: Martin Lowe
Published: (2025-07-01)

Another tail of two sites: activation of the Notch ligand Delta by Mindbomb1
by: Nicole Vüllings, et al.
Published: (2025-03-01)

The delivery and transmembrane transport mechanism of SVCV nanovaccine
by: Han Zhang, et al.
Published: (2025-12-01)

PKCα Phosphorylates FACI to Switch Its Function in Clathrin-mediated Endocytosis to a Presumed Role in Macropinocytosis in Intestinal and Hepatic CellsSummary
by: Yun Cheng, et al.
Published: (2025-01-01)

Membrane identity and GTPase cascades regulated by toggle and cut‐out switches
by: Perla Del Conte‐Zerial, et al.
Published: (2008-07-01)

Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast
by: Ronish Gupta, et al.
Published: (2007-06-01)

IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex
by: Yuqing Lv, et al.
Published: (2025-05-01)

Mannose/stearyl chloride doubly functionalized polyethylenimine as a nucleic acid vaccine carrier to promote macrophage uptake
by: Lu Bai, et al.
Published: (2024-12-01)

The Internalization Pathways of Liposomes, PLGA, and Magnetic Nanoparticles in Neutrophils
by: Anastasiia Garanina, et al.
Published: (2024-09-01)

Revisiting Pathogen Exploitation of Clathrin-Independent Endocytosis: Mechanisms and Implications
by: Oliver Goldmann, et al.
Published: (2025-05-01)

An Adverse Outcome Pathway for food nanomaterial-induced intestinal barrier disruption
by: Deborah Stanco, et al.
Published: (2024-12-01)