Fracture Fusion on Fast‐Forward: Locally Administered Deferoxamine Significantly Enhances Fracture Healing in Animal Models: A Systematic Review and Meta‐Analysis

Fracture Fusion on Fast‐Forward: Locally Administered Deferoxamine Significantly Enhances Fracture Healing in Animal Models: A Systematic Review and Meta‐Analysis

Abstract Fractures, with a yearly incidence of 1.2%, can lead to healing complications in up to 10% of cases. The angiogenic stimulant deferoxamine (DFO) is recognized for enhancing bone healing when administered into the fracture gap. This systematic review with meta‐analysis investigates the effec...

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Bibliographic Details
Main Authors: Daniel Müller, Jens Klotsche, Magdalena B. Kosik, Carsten Perka, Frank Buttgereit, Paula Hoff, Timo Gaber
Format: Article
Language:English
Published: Wiley 2025-02-01
Series:Advanced Science
Subjects:
µCt
bone regeneration
deferoxamine
mouse model
rat model
Online Access:https://doi.org/10.1002/advs.202413290
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