Rational design of lipid nanoparticles for enabling gene therapies

Lipid nanoparticle (LNP) technology is increasingly enabling RNA-based gene therapies that can potentially be used to treat most diseases. Further, these LNP RNA therapeutics can be designed and manufactured in a matter of weeks, allowing personalized medicines that can be produced in a time frame r...

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Bibliographic Details
Main Authors: Cedric A. Brimacombe, Jayesh A. Kulkarni, Miffy H.Y. Cheng, Kevin An, Dominik Witzigmann, Pieter R. Cullis
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Therapy: Methods & Clinical Development
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Online Access:http://www.sciencedirect.com/science/article/pii/S2329050125001135
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