Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy
BACKGROUND: Loperamide is a synthetic piperidine derivative used for the treatment of both acute and chronic diarrhea. Little is known about its safety and risk in pregnancy. Human data are limited to one surveillance study of Michigan Medicaid patients, with 108 women exposed in the first trimester...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2000-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2000/957649 |
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| _version_ | 1832558927290564608 |
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| author | A Einarson P Mastroiacovo J Arnon A Ornoy A Addis H Malm G Koren |
| author_facet | A Einarson P Mastroiacovo J Arnon A Ornoy A Addis H Malm G Koren |
| author_sort | A Einarson |
| collection | DOAJ |
| description | BACKGROUND: Loperamide is a synthetic piperidine derivative used for the treatment of both acute and chronic diarrhea. Little is known about its safety and risk in pregnancy. Human data are limited to one surveillance study of Michigan Medicaid patients, with 108 women exposed in the first trimester. In this study there were six major birth defects, three of which were cardiovascular anomalies. |
| format | Article |
| id | doaj-art-4ce5025d56e44f28b1d7d8bab613438e |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-4ce5025d56e44f28b1d7d8bab613438e2025-02-03T01:31:12ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-0114318518710.1155/2000/957649Prospective, Controlled, Multicentre Study of Loperimide in PregnancyA Einarson0P Mastroiacovo1J Arnon2A Ornoy3A Addis4H Malm5G Koren6The Motherisk Program, The Hospital For Sick Children, University of Toronto, Toronto, Ontario, CanadaBirth Defects Unit and Telefono Rosso, lnstitute of Pediatrics, Catholic University, Rome, ItalyLaboratory of Teratology, Hebrew University, Jerusalem, IsraelLaboratory of Teratology, Hebrew University, Jerusalem, IsraelMario Negri Institute, Milan, ItalyThe Family Federation of Finland, Department of Genetics, Helsinki, FinlandThe Motherisk Program, The Hospital For Sick Children, University of Toronto, Toronto, Ontario, CanadaBACKGROUND: Loperamide is a synthetic piperidine derivative used for the treatment of both acute and chronic diarrhea. Little is known about its safety and risk in pregnancy. Human data are limited to one surveillance study of Michigan Medicaid patients, with 108 women exposed in the first trimester. In this study there were six major birth defects, three of which were cardiovascular anomalies.http://dx.doi.org/10.1155/2000/957649 |
| spellingShingle | A Einarson P Mastroiacovo J Arnon A Ornoy A Addis H Malm G Koren Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy Canadian Journal of Gastroenterology |
| title | Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy |
| title_full | Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy |
| title_fullStr | Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy |
| title_full_unstemmed | Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy |
| title_short | Prospective, Controlled, Multicentre Study of Loperimide in Pregnancy |
| title_sort | prospective controlled multicentre study of loperimide in pregnancy |
| url | http://dx.doi.org/10.1155/2000/957649 |
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