A novel strategy for identifying hepatotoxic constituents in traditional Chinese medicine using dose-normalized intracellular accumulation as a cytotoxicity indicator: a case study of Jinlingzi San
IntroductionHerb-induced liver injury associated with traditional Chinese medicine (TCM) has increasingly attracted scientific attention. However, the rapid and effective methods for elucidating the material basis of hepatotoxicity in TCM are still lacking. This study developed a strategy based on t...
Saved in:
| Main Authors: | Xiaoting Gu, Hanyang Wang, Keran Li, Cuiting Wu, Xin Di |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-05-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1585186/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Validation of an LC-MS/MS Method for the Simultaneous Intracellular Quantification of the CDK4/6 Inhibitor Abemaciclib and the EZH2 Inhibitors GSK126 and Tazemetostat
by: Stefan Senekowitsch, et al.
Published: (2025-03-01) -
Metabolic profiling of Perilla leaves of different colors: insights into metabolite variation and bioactive compound distribution
by: Senouwa Segla Koffi Dossou, et al.
Published: (2025-01-01) -
Sıvı Kromatografisi Sıralı Kütle Spektroskopisi (LC-MS/MS) Tekniği İle Noskapin Ve İlgili Stres Bozunma Bileşiklerinin İncelenmesi Ve Tayini İçin Metot Optimizasyonu
by: Süleyman Gökçe, et al.
Published: (2017-01-01) -
Sıvı Kromatografisi Sıralı Kütle Spektroskopisi (LC-MS/MS) Tekniği İle Noskapin Ve İlgili Stres Bozunma Bileşiklerinin İncelenmesi Ve Tayini İçin Metot Optimizasyonu
by: Süleyman Gökçe, et al.
Published: (2017-01-01) -
Sıvı Kromatografisi Sıralı Kütle Spektroskopisi (LC-MS/MS) Tekniği İle Noskapin Ve İlgili Stres Bozunma Bileşiklerinin İncelenmesi Ve Tayini İçin Metot Optimizasyonu
by: Süleyman Gökçe, et al.
Published: (2017-01-01)