Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction

ABSTRACT Objective To investigate the correlation between non‐invasive cardiac function monitoring indexes and recent adverse prognosis in patients with STEMI. The hemodynamic indexes with high diagnostic value were selected to construct a new risk prediction model combined with GRACE scores, and th...

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Main Authors: Jiayan Xin, Yingwu Liu, Meng Ning, Chong Zhang
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Annals of Noninvasive Electrocardiology
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Online Access:https://doi.org/10.1111/anec.70056
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author Jiayan Xin
Yingwu Liu
Meng Ning
Chong Zhang
author_facet Jiayan Xin
Yingwu Liu
Meng Ning
Chong Zhang
author_sort Jiayan Xin
collection DOAJ
description ABSTRACT Objective To investigate the correlation between non‐invasive cardiac function monitoring indexes and recent adverse prognosis in patients with STEMI. The hemodynamic indexes with high diagnostic value were selected to construct a new risk prediction model combined with GRACE scores, and the efficiency of the new prediction model was evaluated. Methods STEMI patients who met the inclusion and exclusion criteria were selected. All patients were followed for 6 months of major adverse cardiovascular events (MACE). The non‐invasive cardiac function monitoring indexes were analyzed by univariate and multivariate logistic regression. The ROC curve was used to evaluate the accuracy of non‐invasive cardiac function indexes predicting MACE. Then, a new risk prediction model was established and its prediction efficiency was evaluated by ROC curve. Results Patients were divided into MACE group (N = 69) and non‐MACE group (N = 173), stroke volume (SV), cardiac output (CO), cardiac index (CI), cardiac time intervals (CTI), early diastolic filling rate (EDFR), end‐diastolic volume (EDV), and systemic vascular resistance (SVR) were found to be significant predictors of recent MACE events in STEMI patients. Multivariate logistic regression analysis confirmed that indicators of noninvasive cardiac function were independent predictors. In addition, the combination of SV and CTI with the GRACE score has the potential to enhance the predictive accuracy for MACE. Conclusion Non‐invasive hemodynamic indicators SV, CO, CI, CTI, EDFR, EDV and SVR can not only independently predict the risk of recent MACE in patients with STEMI, but can also be used as joint indicators to significantly improve the predictive ability of GRACE score.
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spelling doaj-art-4cdfa62e9dbf4348af137419bcfdfdd42025-08-20T01:49:36ZengWileyAnnals of Noninvasive Electrocardiology1082-720X1542-474X2025-03-01302n/an/a10.1111/anec.70056Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial InfarctionJiayan Xin0Yingwu Liu1Meng Ning2Chong Zhang3The Third Central Clinical College of Tianjin Medical University Tianjin ChinaArtificial Cell Engineering Technology Research Center Tianjin ChinaArtificial Cell Engineering Technology Research Center Tianjin ChinaThe Third Central Clinical College of Tianjin Medical University Tianjin ChinaABSTRACT Objective To investigate the correlation between non‐invasive cardiac function monitoring indexes and recent adverse prognosis in patients with STEMI. The hemodynamic indexes with high diagnostic value were selected to construct a new risk prediction model combined with GRACE scores, and the efficiency of the new prediction model was evaluated. Methods STEMI patients who met the inclusion and exclusion criteria were selected. All patients were followed for 6 months of major adverse cardiovascular events (MACE). The non‐invasive cardiac function monitoring indexes were analyzed by univariate and multivariate logistic regression. The ROC curve was used to evaluate the accuracy of non‐invasive cardiac function indexes predicting MACE. Then, a new risk prediction model was established and its prediction efficiency was evaluated by ROC curve. Results Patients were divided into MACE group (N = 69) and non‐MACE group (N = 173), stroke volume (SV), cardiac output (CO), cardiac index (CI), cardiac time intervals (CTI), early diastolic filling rate (EDFR), end‐diastolic volume (EDV), and systemic vascular resistance (SVR) were found to be significant predictors of recent MACE events in STEMI patients. Multivariate logistic regression analysis confirmed that indicators of noninvasive cardiac function were independent predictors. In addition, the combination of SV and CTI with the GRACE score has the potential to enhance the predictive accuracy for MACE. Conclusion Non‐invasive hemodynamic indicators SV, CO, CI, CTI, EDFR, EDV and SVR can not only independently predict the risk of recent MACE in patients with STEMI, but can also be used as joint indicators to significantly improve the predictive ability of GRACE score.https://doi.org/10.1111/anec.70056acute myocardial infarctioncombined predictive valuehemodynamicsnon‐invasive cardiac function
spellingShingle Jiayan Xin
Yingwu Liu
Meng Ning
Chong Zhang
Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction
Annals of Noninvasive Electrocardiology
acute myocardial infarction
combined predictive value
hemodynamics
non‐invasive cardiac function
title Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction
title_full Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction
title_fullStr Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction
title_full_unstemmed Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction
title_short Predictive Value of Noninvasive Cardiac Function Monitoring Combined With GRACE Score for Short‐Term Outcomes in Patients With ST‐Segment Elevation Myocardial Infarction
title_sort predictive value of noninvasive cardiac function monitoring combined with grace score for short term outcomes in patients with st segment elevation myocardial infarction
topic acute myocardial infarction
combined predictive value
hemodynamics
non‐invasive cardiac function
url https://doi.org/10.1111/anec.70056
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