Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy

Pleuroparenchymal fibroelastosis (PPFE) is a rare progressive interstitial lung disease presenting with predominantly upper-lobe pleural thickening and pulmonary fibrosis. While most cases are idiopathic, it is rarely seen as a complication of infection or following chemotherapy, radiation therapy,...

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Main Authors: Maheema Bhaskar, Owais Tisekar, Sandeep Tandon, Tushar Vora, Bhavin Jankharia
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-01-01
Series:Indian Journal of Medical and Paediatric Oncology
Subjects:
Online Access:http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=3;spage=427;epage=429;aulast=
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author Maheema Bhaskar
Owais Tisekar
Sandeep Tandon
Tushar Vora
Bhavin Jankharia
author_facet Maheema Bhaskar
Owais Tisekar
Sandeep Tandon
Tushar Vora
Bhavin Jankharia
author_sort Maheema Bhaskar
collection DOAJ
description Pleuroparenchymal fibroelastosis (PPFE) is a rare progressive interstitial lung disease presenting with predominantly upper-lobe pleural thickening and pulmonary fibrosis. While most cases are idiopathic, it is rarely seen as a complication of infection or following chemotherapy, radiation therapy, and bone marrow transplant. We describe a case of early onset and rapidly progressive PPFE as a complication of cyclophosphamide chemotherapy.
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institution OA Journals
issn 0971-5851
0975-2129
language English
publishDate 2020-01-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Medical and Paediatric Oncology
spelling doaj-art-4cdeb224a4f647faa608aae9f71f530a2025-08-20T02:38:36ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-21292020-01-0141342742910.4103/ijmpo.ijmpo_85_19Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapyMaheema BhaskarOwais TisekarSandeep TandonTushar VoraBhavin JankhariaPleuroparenchymal fibroelastosis (PPFE) is a rare progressive interstitial lung disease presenting with predominantly upper-lobe pleural thickening and pulmonary fibrosis. While most cases are idiopathic, it is rarely seen as a complication of infection or following chemotherapy, radiation therapy, and bone marrow transplant. We describe a case of early onset and rapidly progressive PPFE as a complication of cyclophosphamide chemotherapy.http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=3;spage=427;epage=429;aulast=cyclophosphamidepleuroparenchymal fibroelastosisupper-lobe fibrosis
spellingShingle Maheema Bhaskar
Owais Tisekar
Sandeep Tandon
Tushar Vora
Bhavin Jankharia
Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
Indian Journal of Medical and Paediatric Oncology
cyclophosphamide
pleuroparenchymal fibroelastosis
upper-lobe fibrosis
title Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
title_full Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
title_fullStr Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
title_full_unstemmed Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
title_short Rapidly progressive pleuro-parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
title_sort rapidly progressive pleuro parenchymal fibroelastosis secondary to cyclophosphamide chemotherapy
topic cyclophosphamide
pleuroparenchymal fibroelastosis
upper-lobe fibrosis
url http://www.ijmpo.org/article.asp?issn=0971-5851;year=2020;volume=41;issue=3;spage=427;epage=429;aulast=
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AT owaistisekar rapidlyprogressivepleuroparenchymalfibroelastosissecondarytocyclophosphamidechemotherapy
AT sandeeptandon rapidlyprogressivepleuroparenchymalfibroelastosissecondarytocyclophosphamidechemotherapy
AT tusharvora rapidlyprogressivepleuroparenchymalfibroelastosissecondarytocyclophosphamidechemotherapy
AT bhavinjankharia rapidlyprogressivepleuroparenchymalfibroelastosissecondarytocyclophosphamidechemotherapy