Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico

The Trypanosomatidae family encompasses around 24 genera of unicellular protozoans, many of which are transmitted by various hematophagous arthropods, particularly members of the Orders Diptera and Hemiptera. Fleas and ticks—an understudied group of ectoparasites—have been shown to be hosts of a wid...

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Main Authors: Héctor M. Zazueta-Islas, Beatriz Salceda-Sánchez, Herón Huerta-Jiménez, Carlos I. Miranda-Caballero, Marlene Solis-Cortés, Yaretzi de la Cruz-Pacheco, Ana Cristina Luquín-García, Laura V. Mondragon-Peña, Jair Reyes-Hernández, José L. Bravo-Ramos, María-Guadalupe Sánchez-Otero, Javier C. Huerta-Peña, Rosa I. Hernández-Herrera, Pablo San Martin-del Angel, André Luiz Rodrigues Roque, Ángel Rodríguez-Moreno, Víctor Sánchez-Cordero, Héctor Abelardo Rodríguez Martínez, Estefania Grostieta, Ingeborg Becker, Sokani Sánchez-Montes
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Language:English
Published: MDPI AG 2024-12-01
Series:Pathogens
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Online Access:https://www.mdpi.com/2076-0817/13/12/1072
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author Héctor M. Zazueta-Islas
Beatriz Salceda-Sánchez
Herón Huerta-Jiménez
Carlos I. Miranda-Caballero
Marlene Solis-Cortés
Yaretzi de la Cruz-Pacheco
Ana Cristina Luquín-García
Laura V. Mondragon-Peña
Jair Reyes-Hernández
José L. Bravo-Ramos
María-Guadalupe Sánchez-Otero
Javier C. Huerta-Peña
Rosa I. Hernández-Herrera
Pablo San Martin-del Angel
André Luiz Rodrigues Roque
Ángel Rodríguez-Moreno
Víctor Sánchez-Cordero
Héctor Abelardo Rodríguez Martínez
Estefania Grostieta
Ingeborg Becker
Sokani Sánchez-Montes
author_facet Héctor M. Zazueta-Islas
Beatriz Salceda-Sánchez
Herón Huerta-Jiménez
Carlos I. Miranda-Caballero
Marlene Solis-Cortés
Yaretzi de la Cruz-Pacheco
Ana Cristina Luquín-García
Laura V. Mondragon-Peña
Jair Reyes-Hernández
José L. Bravo-Ramos
María-Guadalupe Sánchez-Otero
Javier C. Huerta-Peña
Rosa I. Hernández-Herrera
Pablo San Martin-del Angel
André Luiz Rodrigues Roque
Ángel Rodríguez-Moreno
Víctor Sánchez-Cordero
Héctor Abelardo Rodríguez Martínez
Estefania Grostieta
Ingeborg Becker
Sokani Sánchez-Montes
author_sort Héctor M. Zazueta-Islas
collection DOAJ
description The Trypanosomatidae family encompasses around 24 genera of unicellular protozoans, many of which are transmitted by various hematophagous arthropods, particularly members of the Orders Diptera and Hemiptera. Fleas and ticks—an understudied group of ectoparasites—have been shown to be hosts of a wide and crescent variety of trypanosomatid species. Further, fleas and ticks of companion animals have been particularly neglected in trypanosomatid surveillance despite the proximity to human populations and the anthropophagous habits of many of these arthropods, which can potentially act as vectors of zoonotic trypanosomatids. We aimed to identify the presence, characterize the species, and establish the prevalence of Kinetoplastids, including members of the Trypanosomatidae family, in ectoparasites collected from dogs and humans from Mexico. A total of 537 ectoparasite specimens belonging to six ectoparasite taxa (<i>Amblyomma mixtum</i>, <i>A. tenellum</i>, <i>Ctenocephalides felis felis</i>, <i>Pulex simulans</i>, <i>Rhipicephalus linnaei</i>, and <i>Rh. sanguineus</i> s.s.) were collected from 15 States of Mexico. An 800 bp fragment of the 18S-rDNA gene from kinetoplastids was amplified and sequenced. The presence of two agents (<i>Trypanosoma caninum</i> and <i>Parabodo</i> sp.) was detected in <i>R. linnaei</i> ticks and one (<i>Blechomonas lauriereadi</i>) in the cat flea <i>Ct. felis felis</i>. This is the first record of genetic material of kinetoplastid species in ectoparasites from dogs and humans in Mexico.
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spelling doaj-art-4cdd323fa200494fb37aa83e8c9168552025-08-20T02:39:41ZengMDPI AGPathogens2076-08172024-12-011312107210.3390/pathogens13121072Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in MexicoHéctor M. Zazueta-Islas0Beatriz Salceda-Sánchez1Herón Huerta-Jiménez2Carlos I. Miranda-Caballero3Marlene Solis-Cortés4Yaretzi de la Cruz-Pacheco5Ana Cristina Luquín-García6Laura V. Mondragon-Peña7Jair Reyes-Hernández8José L. Bravo-Ramos9María-Guadalupe Sánchez-Otero10Javier C. Huerta-Peña11Rosa I. Hernández-Herrera12Pablo San Martin-del Angel13André Luiz Rodrigues Roque14Ángel Rodríguez-Moreno15Víctor Sánchez-Cordero16Héctor Abelardo Rodríguez Martínez17Estefania Grostieta18Ingeborg Becker19Sokani Sánchez-Montes20Centro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoLaboratorio de Entomología, Instituto de Diagnóstico y Referencia Epidemiológicos, Secretaría de Salud, Mexico City 01480, MexicoLaboratorio de Entomología, Instituto de Diagnóstico y Referencia Epidemiológicos, Secretaría de Salud, Mexico City 01480, MexicoCentro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoCentro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoFacultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoFacultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoFacultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoFacultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoFacultad de Bioanálisis, Región Veracruz, Universidad Veracruzana, Veracruz 91700, MexicoFacultad de Bioanálisis, Región Veracruz, Universidad Veracruzana, Veracruz 91700, MexicoFacultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoLaboratorio de Biotecnología Ambiental, Facultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoLaboratorio de Biotecnología Ambiental, Facultad de Ciencias Biológicas y Agropecuarias, Región Poza Rica-Tuxpan, Universidad Veracruzana, Tuxpan de Rodríguez Cano, Veracruz 92870, MexicoLaboratório de Biologia de Tripanosomatídeos, Instituto Oswaldo Cruz/FIOCRUZ, Rio de Janeiro 21040-900, BrazilLaboratorio de Geografía de la Biodiversidad, Pabellón Nacional de la Biodiversidad Instituto de Biología, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoLaboratorio de Geografía de la Biodiversidad, Pabellón Nacional de la Biodiversidad Instituto de Biología, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoLaboratorio de Investigaciones Anatomopatológicas, Unidad de Medicina Experimental, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoCentro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoCentro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoCentro de Medicina Tropical, División de Investigación, Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City 04510, MexicoThe Trypanosomatidae family encompasses around 24 genera of unicellular protozoans, many of which are transmitted by various hematophagous arthropods, particularly members of the Orders Diptera and Hemiptera. Fleas and ticks—an understudied group of ectoparasites—have been shown to be hosts of a wide and crescent variety of trypanosomatid species. Further, fleas and ticks of companion animals have been particularly neglected in trypanosomatid surveillance despite the proximity to human populations and the anthropophagous habits of many of these arthropods, which can potentially act as vectors of zoonotic trypanosomatids. We aimed to identify the presence, characterize the species, and establish the prevalence of Kinetoplastids, including members of the Trypanosomatidae family, in ectoparasites collected from dogs and humans from Mexico. A total of 537 ectoparasite specimens belonging to six ectoparasite taxa (<i>Amblyomma mixtum</i>, <i>A. tenellum</i>, <i>Ctenocephalides felis felis</i>, <i>Pulex simulans</i>, <i>Rhipicephalus linnaei</i>, and <i>Rh. sanguineus</i> s.s.) were collected from 15 States of Mexico. An 800 bp fragment of the 18S-rDNA gene from kinetoplastids was amplified and sequenced. The presence of two agents (<i>Trypanosoma caninum</i> and <i>Parabodo</i> sp.) was detected in <i>R. linnaei</i> ticks and one (<i>Blechomonas lauriereadi</i>) in the cat flea <i>Ct. felis felis</i>. This is the first record of genetic material of kinetoplastid species in ectoparasites from dogs and humans in Mexico.https://www.mdpi.com/2076-0817/13/12/1072ectoparasites<i>Rhipicephalus sanguineus</i> s.l.<i>Blechomonas lauriereadi</i><i>Parabodo</i> sp.<i>Trypanosoma caninum</i>
spellingShingle Héctor M. Zazueta-Islas
Beatriz Salceda-Sánchez
Herón Huerta-Jiménez
Carlos I. Miranda-Caballero
Marlene Solis-Cortés
Yaretzi de la Cruz-Pacheco
Ana Cristina Luquín-García
Laura V. Mondragon-Peña
Jair Reyes-Hernández
José L. Bravo-Ramos
María-Guadalupe Sánchez-Otero
Javier C. Huerta-Peña
Rosa I. Hernández-Herrera
Pablo San Martin-del Angel
André Luiz Rodrigues Roque
Ángel Rodríguez-Moreno
Víctor Sánchez-Cordero
Héctor Abelardo Rodríguez Martínez
Estefania Grostieta
Ingeborg Becker
Sokani Sánchez-Montes
Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico
Pathogens
ectoparasites
<i>Rhipicephalus sanguineus</i> s.l.
<i>Blechomonas lauriereadi</i>
<i>Parabodo</i> sp.
<i>Trypanosoma caninum</i>
title Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico
title_full Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico
title_fullStr Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico
title_full_unstemmed Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico
title_short Molecular Detection of Kinetoplastid Species in Ticks and Fleas Associated with Dogs and Humans in Mexico
title_sort molecular detection of kinetoplastid species in ticks and fleas associated with dogs and humans in mexico
topic ectoparasites
<i>Rhipicephalus sanguineus</i> s.l.
<i>Blechomonas lauriereadi</i>
<i>Parabodo</i> sp.
<i>Trypanosoma caninum</i>
url https://www.mdpi.com/2076-0817/13/12/1072
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