A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis

We quantify a recent five-category CT histogram based classification of ground glass opacities using a dynamic mathematical model for the spatial-temporal evolution of malignant nodules. Our mathematical model takes the form of a spatially structured partial differential equation with a logistic cro...

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Main Authors: József Z. Farkas, Gary T. Smith, Glenn F. Webb
Format: Article
Language:English
Published: AIMS Press 2018-09-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2018055
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author József Z. Farkas
Gary T. Smith
Glenn F. Webb
author_facet József Z. Farkas
Gary T. Smith
Glenn F. Webb
author_sort József Z. Farkas
collection DOAJ
description We quantify a recent five-category CT histogram based classification of ground glass opacities using a dynamic mathematical model for the spatial-temporal evolution of malignant nodules. Our mathematical model takes the form of a spatially structured partial differential equation with a logistic crowding term. We present the results of extensive simulations and validate our model using patient data obtained from clinical CT images from patients with benign and malignant lesions.
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spelling doaj-art-4cdaede1654549648fd24b496bfebc4b2025-01-24T02:41:02ZengAIMS PressMathematical Biosciences and Engineering1551-00182018-09-011551203122410.3934/mbe.2018055A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysisJózsef Z. Farkas0Gary T. Smith1Glenn F. Webb2Division of Computing Science and Mathematics, University of Stirling, Stirling, FK9 4LA, UKDepartment of Medical Imaging, Department of Veterans Affairs Hospital, Tennessee Valley Healthcare System, Nashville, Tennessee, 37212, USADepartment of Mathematics, Vanderbilt University, Nashville, TN 37240, USAWe quantify a recent five-category CT histogram based classification of ground glass opacities using a dynamic mathematical model for the spatial-temporal evolution of malignant nodules. Our mathematical model takes the form of a spatially structured partial differential equation with a logistic crowding term. We present the results of extensive simulations and validate our model using patient data obtained from clinical CT images from patients with benign and malignant lesions.https://www.aimspress.com/article/doi/10.3934/mbe.2018055medical imagingct scanlogistic partial differential equation
spellingShingle József Z. Farkas
Gary T. Smith
Glenn F. Webb
A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis
Mathematical Biosciences and Engineering
medical imaging
ct scan
logistic partial differential equation
title A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis
title_full A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis
title_fullStr A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis
title_full_unstemmed A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis
title_short A dynamic model of CT scans for quantifying doubling time of ground glass opacities using histogram analysis
title_sort dynamic model of ct scans for quantifying doubling time of ground glass opacities using histogram analysis
topic medical imaging
ct scan
logistic partial differential equation
url https://www.aimspress.com/article/doi/10.3934/mbe.2018055
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