Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review

The present review examines the microbiological aspects of powdered formulae, emphasizing the vulnerability of newborns and infants to foodborne infections. Aim of this review was to recognize and communicate potential risks associated with various bacterial contaminants, contributing to improve the...

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Main Authors: Viviana Fusi, Simone Stella, Cristian Bernardi, Erica Tirloni
Format: Article
Language:English
Published: Elsevier 2025-05-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844025013088
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author Viviana Fusi
Simone Stella
Cristian Bernardi
Erica Tirloni
author_facet Viviana Fusi
Simone Stella
Cristian Bernardi
Erica Tirloni
author_sort Viviana Fusi
collection DOAJ
description The present review examines the microbiological aspects of powdered formulae, emphasizing the vulnerability of newborns and infants to foodborne infections. Aim of this review was to recognize and communicate potential risks associated with various bacterial contaminants, contributing to improve the objective of ensuring the health and safety of infants. Prevalence and levels of bacterial contamination in powdered formulae were explored: data concerning total viable count, spoilage microorganisms such as Enterobacteriaceae, coliforms, Escherichia coli, clostridial spores, Enterococcus, Pseudomonas, mould, and yeast, as well as pathogens including Cronobacter sakazakii, Salmonella spp., Bacillus cereus, Listeria monocytogenes, and Staphylococcus aureus, were collected. The review includes a detailed compilation of outbreaks, predominantly caused by C. sakazakii and Salmonella spp., and notably, a singular case of infant botulism. These pathogens were identified in powdered or prepared formula, utensils, or production facilities, and even when the pathogen itself was not detected a connection with the product was established. Finally, the review contains notifications from Rapid Alert System for Food and Feed concerning microbiological hazards of powdered formulae.
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spelling doaj-art-4cd7da18a3054cbf867b0cd397859fd32025-08-20T03:07:25ZengElsevierHeliyon2405-84402025-05-011110e4292710.1016/j.heliyon.2025.e42927Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A reviewViviana Fusi0Simone Stella1Cristian Bernardi2Erica Tirloni3Corresponding author.; Department of Veterinary Medicine and Animal Sciences, University of Milan, Via dell’Università 6, 26900, Lodi, ItalyDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell’Università 6, 26900, Lodi, ItalyDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell’Università 6, 26900, Lodi, ItalyDepartment of Veterinary Medicine and Animal Sciences, University of Milan, Via dell’Università 6, 26900, Lodi, ItalyThe present review examines the microbiological aspects of powdered formulae, emphasizing the vulnerability of newborns and infants to foodborne infections. Aim of this review was to recognize and communicate potential risks associated with various bacterial contaminants, contributing to improve the objective of ensuring the health and safety of infants. Prevalence and levels of bacterial contamination in powdered formulae were explored: data concerning total viable count, spoilage microorganisms such as Enterobacteriaceae, coliforms, Escherichia coli, clostridial spores, Enterococcus, Pseudomonas, mould, and yeast, as well as pathogens including Cronobacter sakazakii, Salmonella spp., Bacillus cereus, Listeria monocytogenes, and Staphylococcus aureus, were collected. The review includes a detailed compilation of outbreaks, predominantly caused by C. sakazakii and Salmonella spp., and notably, a singular case of infant botulism. These pathogens were identified in powdered or prepared formula, utensils, or production facilities, and even when the pathogen itself was not detected a connection with the product was established. Finally, the review contains notifications from Rapid Alert System for Food and Feed concerning microbiological hazards of powdered formulae.http://www.sciencedirect.com/science/article/pii/S2405844025013088Powdered infant formulaeFollow-on formulaeMicrobiologySafety
spellingShingle Viviana Fusi
Simone Stella
Cristian Bernardi
Erica Tirloni
Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review
Heliyon
Powdered infant formulae
Follow-on formulae
Microbiology
Safety
title Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review
title_full Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review
title_fullStr Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review
title_full_unstemmed Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review
title_short Microbiological characteristics of powdered infant and follow-on formulae and safety concerns: A review
title_sort microbiological characteristics of powdered infant and follow on formulae and safety concerns a review
topic Powdered infant formulae
Follow-on formulae
Microbiology
Safety
url http://www.sciencedirect.com/science/article/pii/S2405844025013088
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AT simonestella microbiologicalcharacteristicsofpowderedinfantandfollowonformulaeandsafetyconcernsareview
AT cristianbernardi microbiologicalcharacteristicsofpowderedinfantandfollowonformulaeandsafetyconcernsareview
AT ericatirloni microbiologicalcharacteristicsofpowderedinfantandfollowonformulaeandsafetyconcernsareview