A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis
We report a rare case of systemic amyloidosis with gastrointestinal and lymph node involvement. A 64-year-old woman was admitted to our hospital with dyspepsia and weight loss. Initial esophagogastroduodenoscopy (EGD) revealed nonspecific findings, and abdominal computed tomography showed necrotizin...
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Korean College of Helicobacter and Upper Gastrointestinal Research
2018-09-01
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| Series: | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
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| Online Access: | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.3.209 |
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| author | Ja In Lee Joon Sung Kim Byung Wook Kim |
| author_facet | Ja In Lee Joon Sung Kim Byung Wook Kim |
| author_sort | Ja In Lee |
| collection | DOAJ |
| description | We report a rare case of systemic amyloidosis with gastrointestinal and lymph node involvement. A 64-year-old woman was admitted to our hospital with dyspepsia and weight loss. Initial esophagogastroduodenoscopy (EGD) revealed nonspecific findings, and abdominal computed tomography showed necrotizing lymphadenopathy at the porta hepatis. Laparoscopic lymph node biopsy was performed under suspicion of tuberculous lymphadenopathy, but a definite diagnosis was not established. Follow-up EGD performed 6 months later revealed multiple telangiectasia-like lesions at the gastric body, and endoscopic biopsy revealed amyloid deposition. Through additional blood and urine protein electrophoresis, the patient was finally diagnosed with systemic amyloidosis associated with multiple myeloma. She was treated with dexamethasone, thalidomide, and bortezomib; however, she died 3 months after diagnosis because of pneumonia and multiple organ failure. |
| format | Article |
| id | doaj-art-4cd258bf819947338dafe648fb00a449 |
| institution | Kabale University |
| issn | 1738-3331 |
| language | English |
| publishDate | 2018-09-01 |
| publisher | Korean College of Helicobacter and Upper Gastrointestinal Research |
| record_format | Article |
| series | The Korean Journal of Helicobacter and Upper Gastrointestinal Research |
| spelling | doaj-art-4cd258bf819947338dafe648fb00a4492025-08-20T03:58:23ZengKorean College of Helicobacter and Upper Gastrointestinal ResearchThe Korean Journal of Helicobacter and Upper Gastrointestinal Research1738-33312018-09-0118320921210.7704/kjhugr.2018.18.3.209kjhugr.2018.18.3.209A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta HepatisJa In Lee0Joon Sung Kim1Byung Wook Kim2Division of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, KoreaDivision of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, KoreaDivision of Gastroenterology, Department of Internal Medicine, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Incheon, KoreaWe report a rare case of systemic amyloidosis with gastrointestinal and lymph node involvement. A 64-year-old woman was admitted to our hospital with dyspepsia and weight loss. Initial esophagogastroduodenoscopy (EGD) revealed nonspecific findings, and abdominal computed tomography showed necrotizing lymphadenopathy at the porta hepatis. Laparoscopic lymph node biopsy was performed under suspicion of tuberculous lymphadenopathy, but a definite diagnosis was not established. Follow-up EGD performed 6 months later revealed multiple telangiectasia-like lesions at the gastric body, and endoscopic biopsy revealed amyloid deposition. Through additional blood and urine protein electrophoresis, the patient was finally diagnosed with systemic amyloidosis associated with multiple myeloma. She was treated with dexamethasone, thalidomide, and bortezomib; however, she died 3 months after diagnosis because of pneumonia and multiple organ failure.http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.3.209AmyloidosisLymphadenopathyMultiple myeloma |
| spellingShingle | Ja In Lee Joon Sung Kim Byung Wook Kim A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis The Korean Journal of Helicobacter and Upper Gastrointestinal Research Amyloidosis Lymphadenopathy Multiple myeloma |
| title | A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis |
| title_full | A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis |
| title_fullStr | A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis |
| title_full_unstemmed | A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis |
| title_short | A Case of Amyloidosis Presenting as Lymphadenopathy at the Porta Hepatis |
| title_sort | case of amyloidosis presenting as lymphadenopathy at the porta hepatis |
| topic | Amyloidosis Lymphadenopathy Multiple myeloma |
| url | http://www.helicojournal.org/journal/view.html?doi=10.7704/kjhugr.2018.18.3.209 |
| work_keys_str_mv | AT jainlee acaseofamyloidosispresentingaslymphadenopathyattheportahepatis AT joonsungkim acaseofamyloidosispresentingaslymphadenopathyattheportahepatis AT byungwookkim acaseofamyloidosispresentingaslymphadenopathyattheportahepatis AT jainlee caseofamyloidosispresentingaslymphadenopathyattheportahepatis AT joonsungkim caseofamyloidosispresentingaslymphadenopathyattheportahepatis AT byungwookkim caseofamyloidosispresentingaslymphadenopathyattheportahepatis |