Nuclear medicine as a tool for diagnosis and targeted cancer therapy
The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide therapy of malignant tumors (radiopharmaceuticals...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2018-03-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1132 |
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| author | V. I. Chernov A. A. Medvedeva I. G. Sinilkin R. V. Zelchan O. D. Bragina E. L. Choynzonov |
| author_facet | V. I. Chernov A. A. Medvedeva I. G. Sinilkin R. V. Zelchan O. D. Bragina E. L. Choynzonov |
| author_sort | V. I. Chernov |
| collection | DOAJ |
| description | The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide therapy of malignant tumors (radiopharmaceuticals that can accumulate in tissues surrounding the tumor; radiopharmaceuticals that can accumulate on the membranes of tumor cells, radiopharmaceuticals that can accumulate in tumor cells, radiopharmaceuticals for sentinel lymph nodes detection). It is shown that the current trends in the development of nuclear medicine are closely related to theranostics (therapy + diagnostics) using radiopharmaceuticals obtained on the basis of a target compound labeled with different isotopes intended for diagnosis or therapy. In nuclear medicine, such tandems are used to individualize and plan of radionuclide therapy. The results of our own research on the development of radiopharmaceuticals for tumor imaging and detection of sentinel lymph nodes are presented. The functional utility of radiopharmaceuticals and the prospects of their clinical use are shown. |
| format | Article |
| id | doaj-art-4cc4129e8dad444784218d57ea40f568 |
| institution | Kabale University |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2018-03-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-4cc4129e8dad444784218d57ea40f5682025-08-20T03:37:47ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842018-03-0117122023110.20538/1682-0363-2018-1-220-231779Nuclear medicine as a tool for diagnosis and targeted cancer therapyV. I. Chernov0A. A. Medvedeva1I. G. Sinilkin2R. V. Zelchan3O. D. Bragina4E. L. Choynzonov5Cancer Research Institute, Tomsk National Research Medical Center (TNRMC), Russian Academy of Science (RAS) ; National Research Tomsk Polytechnic University (NR TPU).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC), Russian Academy of Science (RAS).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC), Russian Academy of Science (RAS).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC), Russian Academy of Science (RAS).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC), Russian Academy of Science (RAS).Cancer Research Institute, Tomsk National Research Medical Center (TNRMC), Russian Academy of Science (RAS) ; National Research Tomsk Polytechnic University (NR TPU).The main trends and prospects of development of nuclear medicine, problems and possible ways of their solution are considered in the article. The main scientific directions in the development of radiopharmaceuticals for the diagnosis and radionuclide therapy of malignant tumors (radiopharmaceuticals that can accumulate in tissues surrounding the tumor; radiopharmaceuticals that can accumulate on the membranes of tumor cells, radiopharmaceuticals that can accumulate in tumor cells, radiopharmaceuticals for sentinel lymph nodes detection). It is shown that the current trends in the development of nuclear medicine are closely related to theranostics (therapy + diagnostics) using radiopharmaceuticals obtained on the basis of a target compound labeled with different isotopes intended for diagnosis or therapy. In nuclear medicine, such tandems are used to individualize and plan of radionuclide therapy. The results of our own research on the development of radiopharmaceuticals for tumor imaging and detection of sentinel lymph nodes are presented. The functional utility of radiopharmaceuticals and the prospects of their clinical use are shown.https://bulletin.ssmu.ru/jour/article/view/1132nuclear medicinemalignant neoplasmsradiopharmaceuticalssentinel lymph nodestheranostics |
| spellingShingle | V. I. Chernov A. A. Medvedeva I. G. Sinilkin R. V. Zelchan O. D. Bragina E. L. Choynzonov Nuclear medicine as a tool for diagnosis and targeted cancer therapy Бюллетень сибирской медицины nuclear medicine malignant neoplasms radiopharmaceuticals sentinel lymph nodes theranostics |
| title | Nuclear medicine as a tool for diagnosis and targeted cancer therapy |
| title_full | Nuclear medicine as a tool for diagnosis and targeted cancer therapy |
| title_fullStr | Nuclear medicine as a tool for diagnosis and targeted cancer therapy |
| title_full_unstemmed | Nuclear medicine as a tool for diagnosis and targeted cancer therapy |
| title_short | Nuclear medicine as a tool for diagnosis and targeted cancer therapy |
| title_sort | nuclear medicine as a tool for diagnosis and targeted cancer therapy |
| topic | nuclear medicine malignant neoplasms radiopharmaceuticals sentinel lymph nodes theranostics |
| url | https://bulletin.ssmu.ru/jour/article/view/1132 |
| work_keys_str_mv | AT vichernov nuclearmedicineasatoolfordiagnosisandtargetedcancertherapy AT aamedvedeva nuclearmedicineasatoolfordiagnosisandtargetedcancertherapy AT igsinilkin nuclearmedicineasatoolfordiagnosisandtargetedcancertherapy AT rvzelchan nuclearmedicineasatoolfordiagnosisandtargetedcancertherapy AT odbragina nuclearmedicineasatoolfordiagnosisandtargetedcancertherapy AT elchoynzonov nuclearmedicineasatoolfordiagnosisandtargetedcancertherapy |