tPA‐GFP is a reliable probe for detecting compound exocytosis in human pancreatic β‐cells
Abstract Pancreatic β‐cells secrete insulin stored in large dense core vesicles (LDCV) by fusion of vesicle and plasma membrane during a process called insulin exocytosis. Insulin secretion is biphasic with a fast first phase and a sustained second phase. Previous studies have pointed out that exocy...
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Main Authors: | Aishwarya A. Makam, Shruti Sharma, Prajwal Nagle, Nandhini M. Sundaram, Vidya Mangala Prasad, Nikhil R. Gandasi |
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Format: | Article |
Language: | English |
Published: |
Wiley
2025-02-01
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Series: | FASEB BioAdvances |
Subjects: | |
Online Access: | https://doi.org/10.1096/fba.2024-00131 |
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