CLINICAL AND LABORATORY FEATURES OF ESSENTIAL THROMBOCYTOSIS AND PRIMARY MYELOFIBROSIS DEPENDING ON JAK2 AND CALR1 MUTATION STATUS

CLINICAL AND LABORATORY FEATURES OF ESSENTIAL THROMBOCYTOSIS AND PRIMARY MYELOFIBROSIS DEPENDING ON JAK2 AND CALR1 MUTATION STATUS

Introduction. JAK2V617F mutation is detected in approximately 50 % of patients with essential thrombocytosis (ET) and primary myelofibrosis (PMF). In 2013 most of the JAK2 negative patients showed mutations in the CALR gene. Diagnostic value of JAK2 and CALR mutations is high, but their prognostic s...

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Main Authors: E. G. lisina, N. T. Siordiya, P. A. Butylin, A. A. Silyutina, N. M. Matyukhina, O. M. Senderova, E. S. Fokina, V. A. Ovsepyan, E. G. Lomaia, A. Yu. Zaritskiy
Format: Article
Language:Russian
Published: ABV-press 2017-10-01
Series:Онкогематология
Subjects:
essential thrombocytosis
myelofibrosis
chronic myeloproliferative diseases
jak2
calr
thrombotic complications
Online Access:https://oncohematology.abvpress.ru/ongm/article/view/253
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