Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer

Abstract Primary liver cancer is a significant global health issue with high incidence and mortality rates worldwide. Accurate diagnosis and classification of its subtypes are crucial for choosing the right treatment options and improving patient outcomes. Contrast-enhanced computed tomography (CECT...

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Main Authors: Jiawei Luo, Xiaoyu Wan, Jinchao Du, Li Liu, Ling Zhao, Xin Peng, Min Wu, Shixin Huang, Xixi Nie
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Data
Online Access:https://doi.org/10.1038/s41597-025-05125-2
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author Jiawei Luo
Xiaoyu Wan
Jinchao Du
Li Liu
Ling Zhao
Xin Peng
Min Wu
Shixin Huang
Xixi Nie
author_facet Jiawei Luo
Xiaoyu Wan
Jinchao Du
Li Liu
Ling Zhao
Xin Peng
Min Wu
Shixin Huang
Xixi Nie
author_sort Jiawei Luo
collection DOAJ
description Abstract Primary liver cancer is a significant global health issue with high incidence and mortality rates worldwide. Accurate diagnosis and classification of its subtypes are crucial for choosing the right treatment options and improving patient outcomes. Contrast-enhanced computed tomography (CECT) is known for its high sensitivity and specificity in diagnosing liver cancer. However, publicly available datasets of liver cancer CECT scans are limited and often do not fully cover all subtypes or include complete CT scan phases. We hypothesize that using 3D CECT images with complete scan phases can help develop and validate diagnostic and segmentation models for primary liver cancer. Therefore, we created a CECT dataset with annotated liver and lesion areas. This dataset includes 278 cases of liver cancer, featuring hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma, along with CECT images from 83 non-liver cancer subjects. It contains over 50,000 layers of liver cancer lesion images. We believe this dataset can offer valuable support for developing and validating models for classifying and segmenting primary liver cancer.
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publishDate 2025-05-01
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spelling doaj-art-4cbcc5439b5a4a03b2e4893b24c0c0192025-08-20T03:09:34ZengNature PortfolioScientific Data2052-44632025-05-011211810.1038/s41597-025-05125-2Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancerJiawei Luo0Xiaoyu Wan1Jinchao Du2Li Liu3Ling Zhao4Xin Peng5Min Wu6Shixin Huang7Xixi Nie8West China Biomedical Big Data Center, West China Hospital; Med-X Center for Informatics, Sichuan UniversitySchool of Communications and Information Engineering, Chongqing University of Posts and TelecommunicationsDepartment of Radiology, Chongqing Hospital of Traditional Chinese MedicineDepartment of Radiology, The People’s Hospital of Yubei District of Chongqing cityDepartment of Radiology, The People’s Hospital of Yubei District of Chongqing cityDepartment of Radiology, The People’s Hospital of Yubei District of Chongqing cityCollege of Biomedical Engineering, Chongqing Medical UniversityDepartment of Scientific Research, The People’s Hospital of Yubei District of Chongqing citySchool of Computer Science and Technology, Chongqing University of Posts and TelecommunicationsAbstract Primary liver cancer is a significant global health issue with high incidence and mortality rates worldwide. Accurate diagnosis and classification of its subtypes are crucial for choosing the right treatment options and improving patient outcomes. Contrast-enhanced computed tomography (CECT) is known for its high sensitivity and specificity in diagnosing liver cancer. However, publicly available datasets of liver cancer CECT scans are limited and often do not fully cover all subtypes or include complete CT scan phases. We hypothesize that using 3D CECT images with complete scan phases can help develop and validate diagnostic and segmentation models for primary liver cancer. Therefore, we created a CECT dataset with annotated liver and lesion areas. This dataset includes 278 cases of liver cancer, featuring hepatocellular carcinoma, intrahepatic cholangiocarcinoma, and combined hepatocellular-cholangiocarcinoma, along with CECT images from 83 non-liver cancer subjects. It contains over 50,000 layers of liver cancer lesion images. We believe this dataset can offer valuable support for developing and validating models for classifying and segmenting primary liver cancer.https://doi.org/10.1038/s41597-025-05125-2
spellingShingle Jiawei Luo
Xiaoyu Wan
Jinchao Du
Li Liu
Ling Zhao
Xin Peng
Min Wu
Shixin Huang
Xixi Nie
Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer
Scientific Data
title Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer
title_full Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer
title_fullStr Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer
title_full_unstemmed Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer
title_short Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer
title_sort comprehensive multi phase 3d contrast enhanced ct imaging for primary liver cancer
url https://doi.org/10.1038/s41597-025-05125-2
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