SDZ MRL 953, A Novel Synthetic Lipid a Analogue, Induces Tolerance to the Lethal Effects of Endotoxin and Enhances Nonspecific Immunity
Despite the availability of potent antimicrobials, shock due to Gram-negative rod sepsis remains an important clinical concern in immunosuppressed patients. Current strategies for treating septic shock by removal of endotoxin (lipopolysaccharides [LPS]) or putative mediators have only been partially...
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Main Authors: | Charles Lam, Eberhard Schütze, Emmanuel Quakyi, Ekke Liehl, Peter Stütz |
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Format: | Article |
Language: | English |
Published: |
Wiley
1992-01-01
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Series: | Canadian Journal of Infectious Diseases |
Online Access: | http://dx.doi.org/10.1155/1992/591894 |
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