Recognition and management of neonatal hemodynamic compromise

Hemodynamic compromise of the neonate can occur in various clinical situations, including but not limited to maladaptation during the early transitional period, sepsis, congenital heart anomalies, hemodynamically significant patent ductus arteriosus, persistent pulmonary hypertension of the newborn,...

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Main Authors: Tai-Wei Wu, Shahab Noori
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Pediatrics and Neonatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1875957220302060
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author Tai-Wei Wu
Shahab Noori
author_facet Tai-Wei Wu
Shahab Noori
author_sort Tai-Wei Wu
collection DOAJ
description Hemodynamic compromise of the neonate can occur in various clinical situations, including but not limited to maladaptation during the early transitional period, sepsis, congenital heart anomalies, hemodynamically significant patent ductus arteriosus, persistent pulmonary hypertension of the newborn, systemic inflammatory diseases such as necrotizing enterocolitis, and dehydration. Despite the handful of advances in neonatal care through ground-breaking clinical trials, the management of neonatal shock is often dependent on the bedside clinician's experience and training without the aid of high-level evidence. However, the recognition for the importance of comprehensive and serial hemodynamic assessment is growing. There is now a wealth of literature investigating the use of functional echocardiography, near-infrared spectroscopy, and noninvasive impedance-based cardiometry to complement common bedside hemodynamic measures such as blood pressure and heart rate measurement. In this review article, the pathophysiology of neonatal hemodynamic compromise is outlined, and concomitant best-evidence management for hemodynamic compromise in the neonate is proposed.
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spelling doaj-art-4cb378eaad8b48a7ad38fa6f5b545f352025-08-20T02:12:41ZengElsevierPediatrics and Neonatology1875-95722021-02-0162S22S2910.1016/j.pedneo.2020.12.007Recognition and management of neonatal hemodynamic compromiseTai-Wei Wu0Shahab Noori1Fetal and Neonatal Institute, Division of Neonatology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USACorresponding author. RDCS, Children's Hospital Los Angeles Division of Neonatology 4650 Sunset Blvd, MS 31, Los Angeles, CA, 90027, USA. Fax: +(323) 361 7927.; Fetal and Neonatal Institute, Division of Neonatology, Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA, USAHemodynamic compromise of the neonate can occur in various clinical situations, including but not limited to maladaptation during the early transitional period, sepsis, congenital heart anomalies, hemodynamically significant patent ductus arteriosus, persistent pulmonary hypertension of the newborn, systemic inflammatory diseases such as necrotizing enterocolitis, and dehydration. Despite the handful of advances in neonatal care through ground-breaking clinical trials, the management of neonatal shock is often dependent on the bedside clinician's experience and training without the aid of high-level evidence. However, the recognition for the importance of comprehensive and serial hemodynamic assessment is growing. There is now a wealth of literature investigating the use of functional echocardiography, near-infrared spectroscopy, and noninvasive impedance-based cardiometry to complement common bedside hemodynamic measures such as blood pressure and heart rate measurement. In this review article, the pathophysiology of neonatal hemodynamic compromise is outlined, and concomitant best-evidence management for hemodynamic compromise in the neonate is proposed.http://www.sciencedirect.com/science/article/pii/S1875957220302060hypotensioninotropepretermshockvasopressor
spellingShingle Tai-Wei Wu
Shahab Noori
Recognition and management of neonatal hemodynamic compromise
Pediatrics and Neonatology
hypotension
inotrope
preterm
shock
vasopressor
title Recognition and management of neonatal hemodynamic compromise
title_full Recognition and management of neonatal hemodynamic compromise
title_fullStr Recognition and management of neonatal hemodynamic compromise
title_full_unstemmed Recognition and management of neonatal hemodynamic compromise
title_short Recognition and management of neonatal hemodynamic compromise
title_sort recognition and management of neonatal hemodynamic compromise
topic hypotension
inotrope
preterm
shock
vasopressor
url http://www.sciencedirect.com/science/article/pii/S1875957220302060
work_keys_str_mv AT taiweiwu recognitionandmanagementofneonatalhemodynamiccompromise
AT shahabnoori recognitionandmanagementofneonatalhemodynamiccompromise