uPAR and cFn as candidate protein biomarkers for identifying low response to rtPA in acute ischemic stroke

uPAR and cFn as candidate protein biomarkers for identifying low response to rtPA in acute ischemic stroke

Abstract Background Recombinant tissue plasminogen activator (rtPA) remains the main therapeutic for acute ischemic stroke (AIS). In clinical practice, the patients with AIS presenting low response to rtPA is commonly observed. Cognizant that the endothelial cell function is impaired in AIS, this st...

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Bibliographic Details
Main Authors: Yilin Wang, Yuyou Huang, Fangfang Li, Ziping Han, Zhenhong Yang, Liyuan Zhong, Lingzhi Li, Haiping Zhao, Junfen Fan, Yangmin Zheng, Cesario Borlongan, Yumin Luo
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Acute ischemic stroke
Outcome
RtPA
UPAR
CFn
Online Access:https://doi.org/10.1186/s40001-025-02772-4
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