Limited Experimental Susceptibility of Post-Smolt Atlantic salmon (<i>Salmo salar</i>) to an Emergent Strain of <i>Vibrio Anguillarum</i> Serotype O3

Limited Experimental Susceptibility of Post-Smolt Atlantic salmon (<i>Salmo salar</i>) to an Emergent Strain of <i>Vibrio Anguillarum</i> Serotype O3

Preliminary evidence has showed an emergent serotype O3 (SO3) strain of <i>Vibrio anguillarum</i> to cause mortality in pre-smolt Atlantic salmon (<i>Salmo salar</i>) by injection with >10<sup>5</sup> colony forming units (cfus). Here, we sought to identify the...

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Bibliographic Details
Main Authors: Demitri Lifgren, Sarah M. Turner, Timothy J. Welch, Deborah Bouchard, Mark P. Polinski
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Aquaculture Journal
Subjects:
Atlantic salmon
<i>Vibro anguillarum</i>
serotype O3
qPCR
susceptibility
Online Access:https://www.mdpi.com/2673-9496/4/4/21
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Summary:Preliminary evidence has showed an emergent serotype O3 (SO3) strain of <i>Vibrio anguillarum</i> to cause mortality in pre-smolt Atlantic salmon (<i>Salmo salar</i>) by injection with >10<sup>5</sup> colony forming units (cfus). Here, we sought to identify the susceptibility of Atlantic salmon post-smolts to this emergent strain by both injection and cohabitation to better understand transmission risk within cultured salmon and possibly between salmon and Atlantic menhaden (<i>Brevoortia tyrannus</i>), where this strain was identified. We identified that although mortality could be induced with a high-dose (>10<sup>6</sup> cfus) intraperitoneal injection of the emergent SO3 strain (cumulative mortality of 40%), post-smolt Atlantic salmon were highly refractory to a low dose (<10<sup>6</sup> cfus; cumulative mortality of 3%) or cohabitation exposure (no mortality). A qPCR assay targeting this strain was developed and analytically validated, revealing the limited presence of bacterial DNA in the spleen of low-dose-injected fish (2/36) and no detections in sampled cohabitants (0/70) across three timepoints during the 27-day challenge. These results suggest that although Atlantic salmon can succumb to high-dose artificial infections with <i>V. anguillarum</i> SO3, the risk of natural transmissibility and susceptibility of Atlantic salmon to this emergent strain is anticipated to be low.
ISSN:2673-9496

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