Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods
The rigid saddle-shaped framework of isosteviol provides a unique host–guest recognition cavity. For the first time, we have utilized isosteviol to construct fluorescent probes 4 and 5, achieving highly selective recognition of maleic acid and fumaric acid. The experimental results indicated that ne...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
|
| Series: | Foods |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2304-8158/14/9/1541 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850278883394322432 |
|---|---|
| author | Xinye Qian Chunling Zheng Fang Zhang |
| author_facet | Xinye Qian Chunling Zheng Fang Zhang |
| author_sort | Xinye Qian |
| collection | DOAJ |
| description | The rigid saddle-shaped framework of isosteviol provides a unique host–guest recognition cavity. For the first time, we have utilized isosteviol to construct fluorescent probes 4 and 5, achieving highly selective recognition of maleic acid and fumaric acid. The experimental results indicated that neither probe 4 nor probe 5 exhibited significant fluorescence changes when exposed to fumaric acid. However, both probes demonstrated distinct ratiometric fluorescence responses upon interaction with maleic acid. For maleic acid, probes 4 and 5 showed detection limits of 4.14 × 10<sup>−6</sup> M and 1.88 × 10<sup>−6</sup> M, respectively. Density functional theory (DFT) calculations and <sup>1</sup>H NMR spectroscopy revealed that probes 4 and 5 formed stable intermolecular hydrogen bonds with maleic acid, contributing to the observed changes in fluorescence signals. Furthermore, maleic acid was successfully detected in starch-rich dietary samples, including potatoes, sweet potatoes, and corn, utilizing the sensing capabilities of probes 4 and 5. In conclusion, probes 4 and 5 hold significant potential for the development of fluorescence-based recognition systems for fumaric acid and maleic acid. |
| format | Article |
| id | doaj-art-4c9518438bef45599fa65dd2b3155697 |
| institution | OA Journals |
| issn | 2304-8158 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Foods |
| spelling | doaj-art-4c9518438bef45599fa65dd2b31556972025-08-20T01:49:18ZengMDPI AGFoods2304-81582025-04-01149154110.3390/foods14091541Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy FoodsXinye Qian0Chunling Zheng1Fang Zhang2College of Food Science and Light Industry, Nanjing Tech University, Nanjing 211800, ChinaCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211800, ChinaCollege of Food Science and Light Industry, Nanjing Tech University, Nanjing 211800, ChinaThe rigid saddle-shaped framework of isosteviol provides a unique host–guest recognition cavity. For the first time, we have utilized isosteviol to construct fluorescent probes 4 and 5, achieving highly selective recognition of maleic acid and fumaric acid. The experimental results indicated that neither probe 4 nor probe 5 exhibited significant fluorescence changes when exposed to fumaric acid. However, both probes demonstrated distinct ratiometric fluorescence responses upon interaction with maleic acid. For maleic acid, probes 4 and 5 showed detection limits of 4.14 × 10<sup>−6</sup> M and 1.88 × 10<sup>−6</sup> M, respectively. Density functional theory (DFT) calculations and <sup>1</sup>H NMR spectroscopy revealed that probes 4 and 5 formed stable intermolecular hydrogen bonds with maleic acid, contributing to the observed changes in fluorescence signals. Furthermore, maleic acid was successfully detected in starch-rich dietary samples, including potatoes, sweet potatoes, and corn, utilizing the sensing capabilities of probes 4 and 5. In conclusion, probes 4 and 5 hold significant potential for the development of fluorescence-based recognition systems for fumaric acid and maleic acid.https://www.mdpi.com/2304-8158/14/9/1541fluorescencemaleic acidfumaric acidisosteviol |
| spellingShingle | Xinye Qian Chunling Zheng Fang Zhang Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods Foods fluorescence maleic acid fumaric acid isosteviol |
| title | Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods |
| title_full | Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods |
| title_fullStr | Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods |
| title_full_unstemmed | Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods |
| title_short | Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods |
| title_sort | ratiometric fluorescent probes based on isosteviol with identification of maleic acid in starchy foods |
| topic | fluorescence maleic acid fumaric acid isosteviol |
| url | https://www.mdpi.com/2304-8158/14/9/1541 |
| work_keys_str_mv | AT xinyeqian ratiometricfluorescentprobesbasedonisosteviolwithidentificationofmaleicacidinstarchyfoods AT chunlingzheng ratiometricfluorescentprobesbasedonisosteviolwithidentificationofmaleicacidinstarchyfoods AT fangzhang ratiometricfluorescentprobesbasedonisosteviolwithidentificationofmaleicacidinstarchyfoods |