Ratiometric Fluorescent Probes Based on Isosteviol with Identification of Maleic Acid in Starchy Foods
The rigid saddle-shaped framework of isosteviol provides a unique host–guest recognition cavity. For the first time, we have utilized isosteviol to construct fluorescent probes 4 and 5, achieving highly selective recognition of maleic acid and fumaric acid. The experimental results indicated that ne...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-04-01
|
| Series: | Foods |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2304-8158/14/9/1541 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Summary: | The rigid saddle-shaped framework of isosteviol provides a unique host–guest recognition cavity. For the first time, we have utilized isosteviol to construct fluorescent probes 4 and 5, achieving highly selective recognition of maleic acid and fumaric acid. The experimental results indicated that neither probe 4 nor probe 5 exhibited significant fluorescence changes when exposed to fumaric acid. However, both probes demonstrated distinct ratiometric fluorescence responses upon interaction with maleic acid. For maleic acid, probes 4 and 5 showed detection limits of 4.14 × 10<sup>−6</sup> M and 1.88 × 10<sup>−6</sup> M, respectively. Density functional theory (DFT) calculations and <sup>1</sup>H NMR spectroscopy revealed that probes 4 and 5 formed stable intermolecular hydrogen bonds with maleic acid, contributing to the observed changes in fluorescence signals. Furthermore, maleic acid was successfully detected in starch-rich dietary samples, including potatoes, sweet potatoes, and corn, utilizing the sensing capabilities of probes 4 and 5. In conclusion, probes 4 and 5 hold significant potential for the development of fluorescence-based recognition systems for fumaric acid and maleic acid. |
|---|---|
| ISSN: | 2304-8158 |