Dose Effect and Mode of Inheritance of Diabetogenic Gene on Mouse Chromosome 11

Dose Effect and Mode of Inheritance of Diabetogenic Gene on Mouse Chromosome 11

The quantitative trait locus (QTL) mapping in segregating crosses of NSY (Nagoya-Shibata-Yasuda) mice, an animal model of type 2 diabetes, with nondiabetic strain C3H/He mice has identified diabetogenic QTLs on multiple chromosomes. The QTL on chromosome 11 (Chr11) (Nidd1n) showing the largest effec...

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Bibliographic Details
Main Authors: Naru Babaya, Hironori Ueda, Shinsuke Noso, Yoshihisa Hiromine, Koji Nojima, Michiko Itoi-Babaya, Misato Kobayashi, Tomomi Fujisawa, Hiroshi Ikegami
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2013/608923
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