Proliferative Verrucous Leukoplakia with Dysplastic Changes
Proliferative verrucous leukoplakia is one of the rare premalignant white lesions with highest conversion rate to malignancy. It grows gradually and irreversibly with multifocal presentation, exophytic and verrucous appearance. This lesion has been reported resistant to all therapeutic approaches i...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Bahria Univerisy Health Sciences, Campus Karachi
2022-07-01
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| Series: | Journal of Bahria University Medical and Dental College |
| Online Access: | https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/953 |
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| _version_ | 1850079709781557248 |
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| author | Sanaa Ahmed Muhammad Nasir M. Sibghatullah Khan Maria Naz Uzma Bukhari |
| author_facet | Sanaa Ahmed Muhammad Nasir M. Sibghatullah Khan Maria Naz Uzma Bukhari |
| author_sort | Sanaa Ahmed |
| collection | DOAJ |
| description |
Proliferative verrucous leukoplakia is one of the rare premalignant white lesions with highest conversion rate to malignancy.
It grows gradually and irreversibly with multifocal presentation, exophytic and verrucous appearance. This lesion has been
reported resistant to all therapeutic approaches including both non-surgical and surgical. Predisposing factors include
female gender in the 6th decade of life. Proliferative verrucous leukoplakia has the highest tendency to neoplastic transformation
and progression to oral squamous cell carcinoma and oral verrucous carcinoma in majority of the cases. The case of
proliferative verrucous lesion clinically appearing benign presented here but on histopathology proven dysplasia in a patient
with the history of smoking which he stopped six years back.
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| format | Article |
| id | doaj-art-4c932322bc19475baaccc9bbe70dd518 |
| institution | DOAJ |
| issn | 2220-7562 2617-9482 |
| language | English |
| publishDate | 2022-07-01 |
| publisher | Bahria Univerisy Health Sciences, Campus Karachi |
| record_format | Article |
| series | Journal of Bahria University Medical and Dental College |
| spelling | doaj-art-4c932322bc19475baaccc9bbe70dd5182025-08-20T02:45:08ZengBahria Univerisy Health Sciences, Campus KarachiJournal of Bahria University Medical and Dental College2220-75622617-94822022-07-01120310.51985/JBUMDC202238Proliferative Verrucous Leukoplakia with Dysplastic ChangesSanaa AhmedMuhammad NasirM. Sibghatullah KhanMaria NazUzma Bukhari Proliferative verrucous leukoplakia is one of the rare premalignant white lesions with highest conversion rate to malignancy. It grows gradually and irreversibly with multifocal presentation, exophytic and verrucous appearance. This lesion has been reported resistant to all therapeutic approaches including both non-surgical and surgical. Predisposing factors include female gender in the 6th decade of life. Proliferative verrucous leukoplakia has the highest tendency to neoplastic transformation and progression to oral squamous cell carcinoma and oral verrucous carcinoma in majority of the cases. The case of proliferative verrucous lesion clinically appearing benign presented here but on histopathology proven dysplasia in a patient with the history of smoking which he stopped six years back. https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/953 |
| spellingShingle | Sanaa Ahmed Muhammad Nasir M. Sibghatullah Khan Maria Naz Uzma Bukhari Proliferative Verrucous Leukoplakia with Dysplastic Changes Journal of Bahria University Medical and Dental College |
| title | Proliferative Verrucous Leukoplakia with Dysplastic Changes |
| title_full | Proliferative Verrucous Leukoplakia with Dysplastic Changes |
| title_fullStr | Proliferative Verrucous Leukoplakia with Dysplastic Changes |
| title_full_unstemmed | Proliferative Verrucous Leukoplakia with Dysplastic Changes |
| title_short | Proliferative Verrucous Leukoplakia with Dysplastic Changes |
| title_sort | proliferative verrucous leukoplakia with dysplastic changes |
| url | https://jbumdc.bahria.edu.pk/index.php/ojs/article/view/953 |
| work_keys_str_mv | AT sanaaahmed proliferativeverrucousleukoplakiawithdysplasticchanges AT muhammadnasir proliferativeverrucousleukoplakiawithdysplasticchanges AT msibghatullahkhan proliferativeverrucousleukoplakiawithdysplasticchanges AT marianaz proliferativeverrucousleukoplakiawithdysplasticchanges AT uzmabukhari proliferativeverrucousleukoplakiawithdysplasticchanges |