The role of alpha 6 integrin in prostate cancer migration and bone pain in a novel xenograft model.

The role of alpha 6 integrin in prostate cancer migration and bone pain in a novel xenograft model.

Of the estimated 565,650 people in the U.S. who will die of cancer in 2008, almost all will have metastasis. Breast, prostate, kidney, thyroid and lung cancers metastasize to the bone. Tumor cells reside within the bone using integrin type cell adhesion receptors and elicit incapacitating bone pain...

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Bibliographic Details
Main Authors: Tamara E King, Sangita C Pawar, Lisa Majuta, Isis C Sroka, Danyel Wynn, Manolis C Demetriou, Raymond B Nagle, Frank Porreca, Anne E Cress
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003535&type=printable
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