A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China

We establish an SEIQRS epidemic model with periodic transmission rate to investigate the spread of seasonal HFMD in Wenzhou. The value of this study lies in two aspects. Mathematically, we show that the global dynamics of the HFMD model can be governed by its reproduction number R0; if R0<1, the...

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Main Authors: Yeting Zhu, Boyang Xu, Xinze Lian, Wang Lin, Zumu Zhou, Weiming Wang
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Abstract and Applied Analysis
Online Access:http://dx.doi.org/10.1155/2014/234509
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author Yeting Zhu
Boyang Xu
Xinze Lian
Wang Lin
Zumu Zhou
Weiming Wang
author_facet Yeting Zhu
Boyang Xu
Xinze Lian
Wang Lin
Zumu Zhou
Weiming Wang
author_sort Yeting Zhu
collection DOAJ
description We establish an SEIQRS epidemic model with periodic transmission rate to investigate the spread of seasonal HFMD in Wenzhou. The value of this study lies in two aspects. Mathematically, we show that the global dynamics of the HFMD model can be governed by its reproduction number R0; if R0<1, the disease-free equilibrium of the model is globally asymptotically stable, which means that the disease will vanish after some period of time; while if R0>1, the model has at least one positive periodic solution and is uniformly persistent, which indicates that HFMD becomes an endemic disease. Epidemiologically, based on the statistical data of HFMD in Wenzhou, we find that the HFMD becomes an endemic disease and will break out in Wenzhou. One of the most interesting findings is that, for controlling the HFMD spread, we must increase the quarantined rate or decrease the treatment cycle.
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spelling doaj-art-4c88b032a46343628487098761a4d8ee2025-08-20T02:38:39ZengWileyAbstract and Applied Analysis1085-33751687-04092014-01-01201410.1155/2014/234509234509A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, ChinaYeting Zhu0Boyang Xu1Xinze Lian2Wang Lin3Zumu Zhou4Weiming Wang5College of Mathematics and Information Science, Wenzhou University, Wenzhou 325035, ChinaCollege of Mathematics and Information Science, Wenzhou University, Wenzhou 325035, ChinaCollege of Mathematics and Information Science, Wenzhou University, Wenzhou 325035, ChinaCollege of Mathematics and Information Science, Wenzhou University, Wenzhou 325035, ChinaWenzhou Center for Disease Control and Prevention, Wenzhou 325000, ChinaCollege of Mathematics and Information Science, Wenzhou University, Wenzhou 325035, ChinaWe establish an SEIQRS epidemic model with periodic transmission rate to investigate the spread of seasonal HFMD in Wenzhou. The value of this study lies in two aspects. Mathematically, we show that the global dynamics of the HFMD model can be governed by its reproduction number R0; if R0<1, the disease-free equilibrium of the model is globally asymptotically stable, which means that the disease will vanish after some period of time; while if R0>1, the model has at least one positive periodic solution and is uniformly persistent, which indicates that HFMD becomes an endemic disease. Epidemiologically, based on the statistical data of HFMD in Wenzhou, we find that the HFMD becomes an endemic disease and will break out in Wenzhou. One of the most interesting findings is that, for controlling the HFMD spread, we must increase the quarantined rate or decrease the treatment cycle.http://dx.doi.org/10.1155/2014/234509
spellingShingle Yeting Zhu
Boyang Xu
Xinze Lian
Wang Lin
Zumu Zhou
Weiming Wang
A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China
Abstract and Applied Analysis
title A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China
title_full A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China
title_fullStr A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China
title_full_unstemmed A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China
title_short A Hand-Foot-and-Mouth Disease Model with Periodic Transmission Rate in Wenzhou, China
title_sort hand foot and mouth disease model with periodic transmission rate in wenzhou china
url http://dx.doi.org/10.1155/2014/234509
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