RAPNO efforts in Brain Tumour Outcomes
Assessing treatment efficacy for brain tumours has evolved since its inception with the introduction of MacDonald’s criteria, which pioneered the utility of imaging to determine an objective and quantifiable response to treatment. This criterion failed to distinguish pseudo response or progression...
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| Format: | Article |
| Language: | English |
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Pakistan Medical Association
2024-04-01
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| Series: | Journal of the Pakistan Medical Association |
| Online Access: | https://jpma.org.pk/index.php/public_html/article/view/20778 |
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| _version_ | 1850098729773694976 |
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| author | Qurat-ul-Ain Virani Zanib Javed Muhammad Shahzad Shamim |
| author_facet | Qurat-ul-Ain Virani Zanib Javed Muhammad Shahzad Shamim |
| author_sort | Qurat-ul-Ain Virani |
| collection | DOAJ |
| description |
Assessing treatment efficacy for brain tumours has evolved
since its inception with the introduction of MacDonald’s
criteria, which pioneered the utility of imaging to
determine an objective and quantifiable response to
treatment. This criterion failed to distinguish pseudo
response or progression from progression and did not
account for non-enhancing disease therefore; the response
assessment in neuro-oncology (RANO) working group was
established to account for these limitations. Since, its
commencement it has worked to determine response
assessment for multiple tumours. As paediatric tumours
exhibit heterogeneous and variable-enhancing
characteristics, the response assessment in paediatric
neuro-oncology (RAPNO) working group was formed to
create separate criteria. Six response criteria have been
published to date, and the article summarizes them.
Keywords: RAPNO, neuro-oncology, response assessment
|
| format | Article |
| id | doaj-art-4c7be40da95f4b2dbc703bf5468009aa |
| institution | DOAJ |
| issn | 0030-9982 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj-art-4c7be40da95f4b2dbc703bf5468009aa2025-08-20T02:40:39ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-04-0174510.47391/JPMA.24-39RAPNO efforts in Brain Tumour OutcomesQurat-ul-Ain Virani0Zanib Javed1Muhammad Shahzad Shamim2Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan.Section of Neurosurgery, Department of Surgery, Aga Khan University, Karachi, Pakistan. Assessing treatment efficacy for brain tumours has evolved since its inception with the introduction of MacDonald’s criteria, which pioneered the utility of imaging to determine an objective and quantifiable response to treatment. This criterion failed to distinguish pseudo response or progression from progression and did not account for non-enhancing disease therefore; the response assessment in neuro-oncology (RANO) working group was established to account for these limitations. Since, its commencement it has worked to determine response assessment for multiple tumours. As paediatric tumours exhibit heterogeneous and variable-enhancing characteristics, the response assessment in paediatric neuro-oncology (RAPNO) working group was formed to create separate criteria. Six response criteria have been published to date, and the article summarizes them. Keywords: RAPNO, neuro-oncology, response assessment https://jpma.org.pk/index.php/public_html/article/view/20778 |
| spellingShingle | Qurat-ul-Ain Virani Zanib Javed Muhammad Shahzad Shamim RAPNO efforts in Brain Tumour Outcomes Journal of the Pakistan Medical Association |
| title | RAPNO efforts in Brain Tumour Outcomes |
| title_full | RAPNO efforts in Brain Tumour Outcomes |
| title_fullStr | RAPNO efforts in Brain Tumour Outcomes |
| title_full_unstemmed | RAPNO efforts in Brain Tumour Outcomes |
| title_short | RAPNO efforts in Brain Tumour Outcomes |
| title_sort | rapno efforts in brain tumour outcomes |
| url | https://jpma.org.pk/index.php/public_html/article/view/20778 |
| work_keys_str_mv | AT quratulainvirani rapnoeffortsinbraintumouroutcomes AT zanibjaved rapnoeffortsinbraintumouroutcomes AT muhammadshahzadshamim rapnoeffortsinbraintumouroutcomes |