Identifying inflammatory phenotypes associated with lung involvement in systemic sclerosis: k-means clustering approach

Identifying inflammatory phenotypes associated with lung involvement in systemic sclerosis: k-means clustering approach

Objectiveto assess the prognostic impact of clusters of hematologic and biochemical indices on interstitial lung disease (ILD) and respiratory damage associated with systemic sclerosis (SSc)MethodsDesign: We conducted a cross-sectional, uncontrolled study. Participants and Settings: a cohort of pati...

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Main Authors: Laura Cano-García, Aimara García-Studer, Sara Manrique-Arija, Fernando Ortiz-Marquez, Rocío Redondo-Rodríguez, Paula Borregón-Garrido, Natalia Mena-Vázquez, Antonio Fernández-Nebro
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
systemic sclerosis
interstitial lung disease
inflammation
C-reactive protein
hematological indices
inflammatory biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1568683/full
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