Investigation of Antimicrobial and Anti-Inflammatory Efficacy of Newly Synthesized Pyrogallol-Coumarin Hybrids: <i>In Vitro</i> and <i>In Silico</i> Studies

Investigation of Antimicrobial and Anti-Inflammatory Efficacy of Newly Synthesized Pyrogallol-Coumarin Hybrids: <i>In Vitro</i> and <i>In Silico</i> Studies

<b>Background:</b> The aim of this study is to present the synthesis of two new compounds with promising antimicrobial and anti-inflammatory properties using precursors that contain pyrogallol and coumarin units. <b>Methods:</b> The characterization of the obtained compounds...

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Main Authors: Dušica Simijonović, Edina Avdović, Sandra Jovičić Milić, Marko Antonijević, Dejan Milenković, Katarina Marković, Mirjana Grujović, Danijela Lj. Stojković, Milan Dekić, Zoran Marković
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Pharmaceutics
Subjects:
pyrogallol-coumarin hybrids
anti-inflammatory effect
antimicrobial activity
molecular docking
molecular dynamics simulations
Online Access:https://www.mdpi.com/1999-4923/16/11/1472
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