The state of the art in anti-aging: plant-based phytochemicals for skin care

Abstract Phytochemicals help mitigate skin aging by scavenging free radicals, modulating key enzymatic pathways, and promoting the skin’s structural integrity. Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase,...

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Main Authors: Merve Tomas, Deniz Günal-Köroğlu, Senem Kamiloglu, Tugba Ozdal, Esra Capanoglu
Format: Article
Language:English
Published: BMC 2025-01-01
Series:Immunity & Ageing
Subjects:
Online Access:https://doi.org/10.1186/s12979-025-00498-9
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author Merve Tomas
Deniz Günal-Köroğlu
Senem Kamiloglu
Tugba Ozdal
Esra Capanoglu
author_facet Merve Tomas
Deniz Günal-Köroğlu
Senem Kamiloglu
Tugba Ozdal
Esra Capanoglu
author_sort Merve Tomas
collection DOAJ
description Abstract Phytochemicals help mitigate skin aging by scavenging free radicals, modulating key enzymatic pathways, and promoting the skin’s structural integrity. Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP-2) linked to aging. Recent research highlights that plant-based phytochemicals can improve skin elasticity, reduce hyperpigmentation, prevent the breakdown of important skin proteins, and support wound healing, making them valuable components for skin care and treatments. This review explores the multifaceted roles of phytochemicals in maintaining and improving skin health, highlighting their mechanisms of action and potential in skin anti-aging innovations.
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language English
publishDate 2025-01-01
publisher BMC
record_format Article
series Immunity & Ageing
spelling doaj-art-4c6ad77a19bd449db5fbf844f4efee8c2025-02-02T12:42:36ZengBMCImmunity & Ageing1742-49332025-01-0122112310.1186/s12979-025-00498-9The state of the art in anti-aging: plant-based phytochemicals for skin careMerve Tomas0Deniz Günal-Köroğlu1Senem Kamiloglu2Tugba Ozdal3Esra Capanoglu4Department of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical UniversityDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical UniversityDepartment of Food Engineering, Faculty of Agriculture, Bursa Uludag UniversityDepartment of Food Engineering, Faculty of Engineering and Natural Sciences, Istanbul Okan UniversityDepartment of Food Engineering, Faculty of Chemical and Metallurgical Engineering, Istanbul Technical UniversityAbstract Phytochemicals help mitigate skin aging by scavenging free radicals, modulating key enzymatic pathways, and promoting the skin’s structural integrity. Carotenoids, vitamins, essential fatty acids, and phenolic compounds work by acting as antioxidants, inhibiting enzymes like hyaluronidase, collagenase, and elastase, which degrade skin structure, and reducing levels of inflammatory markers (IL-6, IL-8, etc.) and matrix metalloproteinases (MMP-1, MMP-2) linked to aging. Recent research highlights that plant-based phytochemicals can improve skin elasticity, reduce hyperpigmentation, prevent the breakdown of important skin proteins, and support wound healing, making them valuable components for skin care and treatments. This review explores the multifaceted roles of phytochemicals in maintaining and improving skin health, highlighting their mechanisms of action and potential in skin anti-aging innovations.https://doi.org/10.1186/s12979-025-00498-9Skin careAnti-agingPhytochemicalsPolyphenolsCarotenoidsFatty acids
spellingShingle Merve Tomas
Deniz Günal-Köroğlu
Senem Kamiloglu
Tugba Ozdal
Esra Capanoglu
The state of the art in anti-aging: plant-based phytochemicals for skin care
Immunity & Ageing
Skin care
Anti-aging
Phytochemicals
Polyphenols
Carotenoids
Fatty acids
title The state of the art in anti-aging: plant-based phytochemicals for skin care
title_full The state of the art in anti-aging: plant-based phytochemicals for skin care
title_fullStr The state of the art in anti-aging: plant-based phytochemicals for skin care
title_full_unstemmed The state of the art in anti-aging: plant-based phytochemicals for skin care
title_short The state of the art in anti-aging: plant-based phytochemicals for skin care
title_sort state of the art in anti aging plant based phytochemicals for skin care
topic Skin care
Anti-aging
Phytochemicals
Polyphenols
Carotenoids
Fatty acids
url https://doi.org/10.1186/s12979-025-00498-9
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