Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation
The aim: to assess the incidence of various forms of pulmonary aspergillosis in patients with cystic fibrosis.Materials and methods. In 2014-2017 yy. in prospective study in different regions of Russia were included 190 patients with cystic fibrosis aged 1 to 37 years. Children – 130, adults – 60....
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2018-07-01
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| Series: | Журнал инфектологии |
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| Online Access: | https://journal.niidi.ru/jofin/article/view/726 |
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| author | Ya. I. Kozlova Yu. V. Borzova O. V. Shadrivova I. E. Suslova O. V. Aak S. M. Ignat’eva T. S. Bogomolova V. A. Ponnaja T. A. Stepanenko A. V. Orlov S. A. Krasovskiy N. N. Klimko |
| author_facet | Ya. I. Kozlova Yu. V. Borzova O. V. Shadrivova I. E. Suslova O. V. Aak S. M. Ignat’eva T. S. Bogomolova V. A. Ponnaja T. A. Stepanenko A. V. Orlov S. A. Krasovskiy N. N. Klimko |
| author_sort | Ya. I. Kozlova |
| collection | DOAJ |
| description | The aim: to assess the incidence of various forms of pulmonary aspergillosis in patients with cystic fibrosis.Materials and methods. In 2014-2017 yy. in prospective study in different regions of Russia were included 190 patients with cystic fibrosis aged 1 to 37 years. Children – 130, adults – 60. All patients underwent allergy (skin tests with fungal allergens, total IgE level, specific IgE to fungal allergens) and mycology (microscopy and cultural investigations of respiratory biomaterials) testing. Chest computed tomography was performed according to the indications.Results. The incidence of fungal sensitization in patients with cystic fibrosis was 57%, to Aspergillus spp. – 27%. The incidence of allergic bronchopulmonary aspergillosis was 5,7%, chronic lung aspergillosis – 4,2%, invasive aspergillosis developed in one patient (0,5%) during immunosuppressive therapy after liver transplantation.Conclusion. The incidence of pulmonary aspergillosis in patients with cystic fibrosis in the Russian Federation was first determined (10.5%). Mycology testing is indicated for patients with cystic fibrosis for early treatment of different variants of pulmonary aspergillosis. |
| format | Article |
| id | doaj-art-4c68e44e185d46ba9ec06ffc365ea592 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2018-07-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-4c68e44e185d46ba9ec06ffc365ea5922025-08-20T03:44:24ZrusJournal InfectologyЖурнал инфектологии2072-67322018-07-01102485410.22625/2072-6732-2018-10-2-48-54636Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian FederationYa. I. Kozlova0Yu. V. Borzova1O. V. Shadrivova2I. E. Suslova3O. V. Aak4S. M. Ignat’eva5T. S. Bogomolova6V. A. Ponnaja7T. A. Stepanenko8A. V. Orlov9S. A. Krasovskiy10N. N. Klimko11North-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovNorth-Western State Medical University named after I.I. MechnikovMultidisciplinary City Hospital № 2North-Western State Medical University named after I.I. Mechnikov Saint Olga Children’s City Hospital № 4Science Research Institute of PulmonologyNorth-Western State Medical University named after I.I. MechnikovThe aim: to assess the incidence of various forms of pulmonary aspergillosis in patients with cystic fibrosis.Materials and methods. In 2014-2017 yy. in prospective study in different regions of Russia were included 190 patients with cystic fibrosis aged 1 to 37 years. Children – 130, adults – 60. All patients underwent allergy (skin tests with fungal allergens, total IgE level, specific IgE to fungal allergens) and mycology (microscopy and cultural investigations of respiratory biomaterials) testing. Chest computed tomography was performed according to the indications.Results. The incidence of fungal sensitization in patients with cystic fibrosis was 57%, to Aspergillus spp. – 27%. The incidence of allergic bronchopulmonary aspergillosis was 5,7%, chronic lung aspergillosis – 4,2%, invasive aspergillosis developed in one patient (0,5%) during immunosuppressive therapy after liver transplantation.Conclusion. The incidence of pulmonary aspergillosis in patients with cystic fibrosis in the Russian Federation was first determined (10.5%). Mycology testing is indicated for patients with cystic fibrosis for early treatment of different variants of pulmonary aspergillosis.https://journal.niidi.ru/jofin/article/view/726cystic fibrosislung aspergillosisallergic bronchopulmonary aspergillosisaspergillus |
| spellingShingle | Ya. I. Kozlova Yu. V. Borzova O. V. Shadrivova I. E. Suslova O. V. Aak S. M. Ignat’eva T. S. Bogomolova V. A. Ponnaja T. A. Stepanenko A. V. Orlov S. A. Krasovskiy N. N. Klimko Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation Журнал инфектологии cystic fibrosis lung aspergillosis allergic bronchopulmonary aspergillosis aspergillus |
| title | Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation |
| title_full | Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation |
| title_fullStr | Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation |
| title_full_unstemmed | Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation |
| title_short | Pulmonary Aspergillosis in Patients with Cystic Fibrosis in Russian Federation |
| title_sort | pulmonary aspergillosis in patients with cystic fibrosis in russian federation |
| topic | cystic fibrosis lung aspergillosis allergic bronchopulmonary aspergillosis aspergillus |
| url | https://journal.niidi.ru/jofin/article/view/726 |
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