Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting
Objective. To assess the progression of carotid artery (CA) stenoses, the relationship to cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass surgery (CABG).Materials and methods. The prospective study included 152 patients, males, medi...
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Open Systems Publication
2024-04-01
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| Series: | Лечащий Врач |
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| Online Access: | https://journal.lvrach.ru/jour/article/view/1203 |
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| author | I. D. Syrova I. V. Tarasova I. S. Lozhkin A. S. Sosnina O. V. Maleva O. A. Trubnikova |
| author_facet | I. D. Syrova I. V. Tarasova I. S. Lozhkin A. S. Sosnina O. V. Maleva O. A. Trubnikova |
| author_sort | I. D. Syrova |
| collection | DOAJ |
| description | Objective. To assess the progression of carotid artery (CA) stenoses, the relationship to cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass surgery (CABG).Materials and methods. The prospective study included 152 patients, males, median age 57 years, of whom 37% had identified < 50% СA stenosis. Neuropsychological screening, duplex scanning of brachiocephalic arteries with colored Doppler blood flow mapping and lipid metabolism parameters evaluation were performed in all patients before and at 5-7 years after surgery. Statistical analysis was performed using the Statistica 10 program (StatSoft, Inc., USA).Results. It was found that the number of patients with CA stenosis increased to 57%, the incidence of acute ischemic stroke was 5% cases, dementia – 2.5% at 5-7 years after CABG. Also, in the group of CA stenoses, the number of cases of mild cognitive impairment increased from 18% to 23%. Only a small proportion of patients reached the target lipid concentrations, and none of patients with CA stenoses reached the target level of LDL. One-third of all patients examined at 5-7 years after CABG refused to take statins.Conclusion. In the long-term postoperative period of CABG (after 5-7 years) there was an increase in the number of patients with CA stenoses, some patients had ischemic strokes and dementia. At the same time, only a small proportion of patients with lipid was able to reach the optimal values recommended for CABG patients, and patients with CA stenoses were unable to reach the target cholesterol LDL concentrations. |
| format | Article |
| id | doaj-art-4c6611646dd34ff58f61fa4c3b0447af |
| institution | Kabale University |
| issn | 1560-5175 2687-1181 |
| language | Russian |
| publishDate | 2024-04-01 |
| publisher | Open Systems Publication |
| record_format | Article |
| series | Лечащий Врач |
| spelling | doaj-art-4c6611646dd34ff58f61fa4c3b0447af2025-08-20T03:37:06ZrusOpen Systems PublicationЛечащий Врач1560-51752687-11812024-04-0103475310.51793/OS.2024.27.3.0071191Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass graftingI. D. Syrova0I. V. Tarasova1I. S. Lozhkin2A. S. Sosnina3O. V. Maleva4O. A. Trubnikova5Federal State Budgetary Scientific Institution Scientific Research Institute of Complex Issues of Cardiovascular Diseases of the Ministry of Science and Higher Education of the Russian FederationFederal State Budgetary Scientific Institution Scientific Research Institute of Complex Issues of Cardiovascular Diseases of the Ministry of Science and Higher Education of the Russian FederationFederal State Budgetary Scientific Institution Scientific Research Institute of Complex Issues of Cardiovascular Diseases of the Ministry of Science and Higher Education of the Russian FederationFederal State Budgetary Scientific Institution Scientific Research Institute of Complex Issues of Cardiovascular Diseases of the Ministry of Science and Higher Education of the Russian FederationFederal State Budgetary Scientific Institution Scientific Research Institute of Complex Issues of Cardiovascular Diseases of the Ministry of Science and Higher Education of the Russian FederationFederal State Budgetary Scientific Institution Scientific Research Institute of Complex Issues of Cardiovascular Diseases of the Ministry of Science and Higher Education of the Russian FederationObjective. To assess the progression of carotid artery (CA) stenoses, the relationship to cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass surgery (CABG).Materials and methods. The prospective study included 152 patients, males, median age 57 years, of whom 37% had identified < 50% СA stenosis. Neuropsychological screening, duplex scanning of brachiocephalic arteries with colored Doppler blood flow mapping and lipid metabolism parameters evaluation were performed in all patients before and at 5-7 years after surgery. Statistical analysis was performed using the Statistica 10 program (StatSoft, Inc., USA).Results. It was found that the number of patients with CA stenosis increased to 57%, the incidence of acute ischemic stroke was 5% cases, dementia – 2.5% at 5-7 years after CABG. Also, in the group of CA stenoses, the number of cases of mild cognitive impairment increased from 18% to 23%. Only a small proportion of patients reached the target lipid concentrations, and none of patients with CA stenoses reached the target level of LDL. One-third of all patients examined at 5-7 years after CABG refused to take statins.Conclusion. In the long-term postoperative period of CABG (after 5-7 years) there was an increase in the number of patients with CA stenoses, some patients had ischemic strokes and dementia. At the same time, only a small proportion of patients with lipid was able to reach the optimal values recommended for CABG patients, and patients with CA stenoses were unable to reach the target cholesterol LDL concentrations.https://journal.lvrach.ru/jour/article/view/1203coronary bypass surgerycarotid artery stenosiscognitive functionscholesterolcerebrovascular events |
| spellingShingle | I. D. Syrova I. V. Tarasova I. S. Lozhkin A. S. Sosnina O. V. Maleva O. A. Trubnikova Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting Лечащий Врач coronary bypass surgery carotid artery stenosis cognitive functions cholesterol cerebrovascular events |
| title | Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting |
| title_full | Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting |
| title_fullStr | Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting |
| title_full_unstemmed | Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting |
| title_short | Assessment of the progression of carotid artery stenoses, the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long-term period of coronary artery bypass grafting |
| title_sort | assessment of the progression of carotid artery stenoses the relationship with cerebrovascular events and lipid metabolism disorders in patients in the long term period of coronary artery bypass grafting |
| topic | coronary bypass surgery carotid artery stenosis cognitive functions cholesterol cerebrovascular events |
| url | https://journal.lvrach.ru/jour/article/view/1203 |
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