Iodide n,π-chelate complexes of platinum(II) based on N-allyl substituted thioureas and their effect on the activity of hepatobiliary system enzymes in comparison with chloride analogs

Iodide n,π-chelate complexes of platinum(II) based on N-allyl substituted thioureas and their effect on the activity of hepatobiliary system enzymes in comparison with chloride analogs

The search for new effective drugs in the treatment of neoplasm remains relevant even today, since the adaptation of transformed cells to the action of classical drugs contributes to the emergence of drug resistance­. This applies to a number of classic chemotherapy drugs of the platinum series, in...

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Bibliographic Details
Main Authors: V. Orysyk, L. Garmanchuk, S. Orysyk, Yu. Zborovskii, S. Shishkina, I. Stupak, P. Novikova, D. Ostapchenko, N. Khranovska, V. Pekhnyo, M. Vovk
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2024-06-01
Series:The Ukrainian Biochemical Journal
Subjects:
alanine aminotransferase
aspartate aminotransferase
gammaglutamyltranspeptidase
lactate dehydrogenase
nmr spectroscopy
n‚π-chelates
thioureas
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2024/06/Orysyk_96_3.pdf
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