Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2025-01-01
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| Series: | PLoS ONE |
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186880/?tool=EBI |
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| author | Spencer C. Wei Aaron J. Cantor Jack Walleshauser Rina Mepani Kory Melton Ashil Bans Prachi Khekare Suhani Gupta Jonathan Wang Craig Soares Radwan Kiwan Jieun Lee Shannon McCawley Vihasi Jani Weng In Leong Pawan K. Shahi Jean Chan Pierre Boivin Peter Otoupal Bikash R. Pattnaik David M. Gamm Krishanu Saha Benjamin G. Gowen Mary Haak-Frendscho Mary J. Janatpour Adam P. Silverman |
| author_facet | Spencer C. Wei Aaron J. Cantor Jack Walleshauser Rina Mepani Kory Melton Ashil Bans Prachi Khekare Suhani Gupta Jonathan Wang Craig Soares Radwan Kiwan Jieun Lee Shannon McCawley Vihasi Jani Weng In Leong Pawan K. Shahi Jean Chan Pierre Boivin Peter Otoupal Bikash R. Pattnaik David M. Gamm Krishanu Saha Benjamin G. Gowen Mary Haak-Frendscho Mary J. Janatpour Adam P. Silverman |
| author_sort | Spencer C. Wei |
| collection | DOAJ |
| format | Article |
| id | doaj-art-4c5976beaa5249cdbef17b4a592e1602 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-4c5976beaa5249cdbef17b4a592e16022025-08-20T02:22:05ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01206Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicinesSpencer C. WeiAaron J. CantorJack WalleshauserRina MepaniKory MeltonAshil BansPrachi KhekareSuhani GuptaJonathan WangCraig SoaresRadwan KiwanJieun LeeShannon McCawleyVihasi JaniWeng In LeongPawan K. ShahiJean ChanPierre BoivinPeter OtoupalBikash R. PattnaikDavid M. GammKrishanu SahaBenjamin G. GowenMary Haak-FrendschoMary J. JanatpourAdam P. Silvermanhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186880/?tool=EBI |
| spellingShingle | Spencer C. Wei Aaron J. Cantor Jack Walleshauser Rina Mepani Kory Melton Ashil Bans Prachi Khekare Suhani Gupta Jonathan Wang Craig Soares Radwan Kiwan Jieun Lee Shannon McCawley Vihasi Jani Weng In Leong Pawan K. Shahi Jean Chan Pierre Boivin Peter Otoupal Bikash R. Pattnaik David M. Gamm Krishanu Saha Benjamin G. Gowen Mary Haak-Frendscho Mary J. Janatpour Adam P. Silverman Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines PLoS ONE |
| title | Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
| title_full | Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
| title_fullStr | Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
| title_full_unstemmed | Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
| title_short | Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
| title_sort | evaluation of subretinally delivered cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12186880/?tool=EBI |
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