Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes

Porphyrinoids are suitable sensitive materials for potentiometric electronic tongues. In this paper, we take advantage of these properties to develop an electronic tongue using an extended-gate field-effect transistor as a signal transducer. The sensitive films were made of different porphyrins and...

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Main Authors: Kishore Pushparaj, Lorena Di Zazzo, Valerio Allegra, Rosamaria Capuano, Alexandro Catini, Gabriele Magna, Roberto Paolesse, Corrado Di Natale
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Chemosensors
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Online Access:https://www.mdpi.com/2227-9040/13/3/108
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author Kishore Pushparaj
Lorena Di Zazzo
Valerio Allegra
Rosamaria Capuano
Alexandro Catini
Gabriele Magna
Roberto Paolesse
Corrado Di Natale
author_facet Kishore Pushparaj
Lorena Di Zazzo
Valerio Allegra
Rosamaria Capuano
Alexandro Catini
Gabriele Magna
Roberto Paolesse
Corrado Di Natale
author_sort Kishore Pushparaj
collection DOAJ
description Porphyrinoids are suitable sensitive materials for potentiometric electronic tongues. In this paper, we take advantage of these properties to develop an electronic tongue using an extended-gate field-effect transistor as a signal transducer. The sensitive films were made of different porphyrins and corroles electropolymerized in situ onto laser-induced graphene electrodes. The electronic tongue was duly characterized with respect to ascorbic acid, a common natural antioxidant. The sensors were shown to be sensitive and selective with respect to common interferents, such as dopamine and uric acid. Finally, the sensors were tested to detect ascorbic acid in artificial tears.
format Article
id doaj-art-4c4d8c31b430420db41520fa1df6080e
institution DOAJ
issn 2227-9040
language English
publishDate 2025-03-01
publisher MDPI AG
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series Chemosensors
spelling doaj-art-4c4d8c31b430420db41520fa1df6080e2025-08-20T02:42:40ZengMDPI AGChemosensors2227-90402025-03-0113310810.3390/chemosensors13030108Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene ElectrodesKishore Pushparaj0Lorena Di Zazzo1Valerio Allegra2Rosamaria Capuano3Alexandro Catini4Gabriele Magna5Roberto Paolesse6Corrado Di Natale7Department of Electronic Engineering, University of Rome Tor Vergata, Via del Politecnico 1, 00133 Rome, ItalyDepartment of Chemical Science and Technology, University of Rome Tor Vergata via della Ricerca Scientifica, 00133 Rome, ItalyDepartment of Electronic Engineering, University of Rome Tor Vergata, Via del Politecnico 1, 00133 Rome, ItalyDepartment of Electronic Engineering, University of Rome Tor Vergata, Via del Politecnico 1, 00133 Rome, ItalyDepartment of Electronic Engineering, University of Rome Tor Vergata, Via del Politecnico 1, 00133 Rome, ItalyDepartment of Chemical Science and Technology, University of Rome Tor Vergata via della Ricerca Scientifica, 00133 Rome, ItalyDepartment of Chemical Science and Technology, University of Rome Tor Vergata via della Ricerca Scientifica, 00133 Rome, ItalyDepartment of Electronic Engineering, University of Rome Tor Vergata, Via del Politecnico 1, 00133 Rome, ItalyPorphyrinoids are suitable sensitive materials for potentiometric electronic tongues. In this paper, we take advantage of these properties to develop an electronic tongue using an extended-gate field-effect transistor as a signal transducer. The sensitive films were made of different porphyrins and corroles electropolymerized in situ onto laser-induced graphene electrodes. The electronic tongue was duly characterized with respect to ascorbic acid, a common natural antioxidant. The sensors were shown to be sensitive and selective with respect to common interferents, such as dopamine and uric acid. Finally, the sensors were tested to detect ascorbic acid in artificial tears.https://www.mdpi.com/2227-9040/13/3/108porphyrinoidsEGFETlaser-induced grapheneelectropolymerizationascorbic acidhuman tears
spellingShingle Kishore Pushparaj
Lorena Di Zazzo
Valerio Allegra
Rosamaria Capuano
Alexandro Catini
Gabriele Magna
Roberto Paolesse
Corrado Di Natale
Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes
Chemosensors
porphyrinoids
EGFET
laser-induced graphene
electropolymerization
ascorbic acid
human tears
title Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes
title_full Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes
title_fullStr Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes
title_full_unstemmed Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes
title_short Detection of Ascorbic Acid in Tears with an Extended-Gate Field-Effect Transistor-Based Electronic Tongue Made of Electropolymerized Porphyrinoids on Laser-Induced Graphene Electrodes
title_sort detection of ascorbic acid in tears with an extended gate field effect transistor based electronic tongue made of electropolymerized porphyrinoids on laser induced graphene electrodes
topic porphyrinoids
EGFET
laser-induced graphene
electropolymerization
ascorbic acid
human tears
url https://www.mdpi.com/2227-9040/13/3/108
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