Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis

Background and Objective. The Bispectral Index (BIS) is utilized to guide the depth of anesthesia monitoring during surgical procedures. However, conflicting results regarding the benefits of BIS for depth of anesthesia monitoring have been reported in numerous studies. The purpose of this meta-anal...

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Main Authors: Yichun Gu, Jiajun Hao, Jiangna Wang, Peng Liang, Xinyi Peng, Xiaoxiao Qin, Yunwei Zhang, Da He
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Anesthesiology Research and Practice
Online Access:http://dx.doi.org/10.1155/2024/5555481
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author Yichun Gu
Jiajun Hao
Jiangna Wang
Peng Liang
Xinyi Peng
Xiaoxiao Qin
Yunwei Zhang
Da He
author_facet Yichun Gu
Jiajun Hao
Jiangna Wang
Peng Liang
Xinyi Peng
Xiaoxiao Qin
Yunwei Zhang
Da He
author_sort Yichun Gu
collection DOAJ
description Background and Objective. The Bispectral Index (BIS) is utilized to guide the depth of anesthesia monitoring during surgical procedures. However, conflicting results regarding the benefits of BIS for depth of anesthesia monitoring have been reported in numerous studies. The purpose of this meta-analysis and systematic review was to assess the effectiveness of BIS for depth of anesthesia monitoring. Search Methods. A systematic search of Ovid-MEDLINE, Cochrane, and PubMed was conducted from inception to April 20, 2023. Clinical trial registers and grey literature were also searched, and reference lists of included studies, as well as related review articles, were manually reviewed. Selection Criteria. The inclusion criteria were randomized controlled trials without gender or age restrictions. The control groups used conventional monitoring, while the intervention groups utilized BIS monitoring. The exclusion criteria included duplicates, reviews, animal studies, unclear outcomes, and incomplete data. Data Collection and Analysis. Two independent reviewers screened the literature, extracted data, and assessed methodological quality, with analyses conducted using R 4.0 software. Main Results. Forty studies were included. In comparison to the conventional depth of anesthesia monitoring, BIS monitoring reduced the postoperative cognitive dysfunction risk (RR = 0.85, 95% CI: 0.73∼0.99, P=0.04), shortened the eye-opening time (MD = −1.34, 95% CI: −2.06∼−0.61, P<0.01), orientation recovery time (MD = −1.99, 95% CI: −3.62∼−0.36, P=0.02), extubation time (MD = −2.54, 95% CI: −3.50∼−1.58, P<0.01), and postanesthesia care unit stay time (MD = −7.11, 95% CI: −12.67∼−1.55, P=0.01) and lowered the anesthesia drug dosage (SMD = −0.39, 95% CI: −0.63∼−0.15, P<0.01).​ Conclusion. BIS can be used to effectively monitor the depth of anesthesia. Its use in general anesthesia enhances the effectiveness of both patient care and surgical procedures.
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spelling doaj-art-4c4b72c834884970838751cdaca7dc802025-08-20T02:43:33ZengWileyAnesthesiology Research and Practice1687-69702024-01-01202410.1155/2024/5555481Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-AnalysisYichun Gu0Jiajun Hao1Jiangna Wang2Peng Liang3Xinyi Peng4Xiaoxiao Qin5Yunwei Zhang6Da He7Shanghai Health Development Research CenterSchool of Public HealthJiangxi University of Chinese MedicineDepartment of AnesthesiologyDepartment of Health ManagementShanghai Health Development Research CenterShanghai Health Development Research CenterShanghai Health Development Research CenterBackground and Objective. The Bispectral Index (BIS) is utilized to guide the depth of anesthesia monitoring during surgical procedures. However, conflicting results regarding the benefits of BIS for depth of anesthesia monitoring have been reported in numerous studies. The purpose of this meta-analysis and systematic review was to assess the effectiveness of BIS for depth of anesthesia monitoring. Search Methods. A systematic search of Ovid-MEDLINE, Cochrane, and PubMed was conducted from inception to April 20, 2023. Clinical trial registers and grey literature were also searched, and reference lists of included studies, as well as related review articles, were manually reviewed. Selection Criteria. The inclusion criteria were randomized controlled trials without gender or age restrictions. The control groups used conventional monitoring, while the intervention groups utilized BIS monitoring. The exclusion criteria included duplicates, reviews, animal studies, unclear outcomes, and incomplete data. Data Collection and Analysis. Two independent reviewers screened the literature, extracted data, and assessed methodological quality, with analyses conducted using R 4.0 software. Main Results. Forty studies were included. In comparison to the conventional depth of anesthesia monitoring, BIS monitoring reduced the postoperative cognitive dysfunction risk (RR = 0.85, 95% CI: 0.73∼0.99, P=0.04), shortened the eye-opening time (MD = −1.34, 95% CI: −2.06∼−0.61, P<0.01), orientation recovery time (MD = −1.99, 95% CI: −3.62∼−0.36, P=0.02), extubation time (MD = −2.54, 95% CI: −3.50∼−1.58, P<0.01), and postanesthesia care unit stay time (MD = −7.11, 95% CI: −12.67∼−1.55, P=0.01) and lowered the anesthesia drug dosage (SMD = −0.39, 95% CI: −0.63∼−0.15, P<0.01).​ Conclusion. BIS can be used to effectively monitor the depth of anesthesia. Its use in general anesthesia enhances the effectiveness of both patient care and surgical procedures.http://dx.doi.org/10.1155/2024/5555481
spellingShingle Yichun Gu
Jiajun Hao
Jiangna Wang
Peng Liang
Xinyi Peng
Xiaoxiao Qin
Yunwei Zhang
Da He
Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis
Anesthesiology Research and Practice
title Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis
title_full Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis
title_fullStr Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis
title_full_unstemmed Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis
title_short Effectiveness Assessment of Bispectral Index Monitoring Compared with Conventional Monitoring in General Anesthesia: A Systematic Review and Meta-Analysis
title_sort effectiveness assessment of bispectral index monitoring compared with conventional monitoring in general anesthesia a systematic review and meta analysis
url http://dx.doi.org/10.1155/2024/5555481
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