Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial
Mesh grafting and Meek micrografting are split-thickness skin graft expansion techniques. This study aimed to compare the effectiveness of Meek and Mesh expansion ratios 1:2 and 1:3 in smaller wounds. An intra-patient randomized controlled trial was conducted at two burn centers (the Netherlands and...
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MDPI AG
2025-05-01
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| Series: | European Burn Journal |
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| Online Access: | https://www.mdpi.com/2673-1991/6/2/26 |
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| author | Danielle Rijpma Karel Claes Anouk Pijpe Henk Hoeksema Ignace De Decker Jozef Verbelen Matthea Stoop Kimberly De Mey Febe Hoste Paul van Zuijlen Stan Monstrey Annebeth Meij-de Vries |
| author_facet | Danielle Rijpma Karel Claes Anouk Pijpe Henk Hoeksema Ignace De Decker Jozef Verbelen Matthea Stoop Kimberly De Mey Febe Hoste Paul van Zuijlen Stan Monstrey Annebeth Meij-de Vries |
| author_sort | Danielle Rijpma |
| collection | DOAJ |
| description | Mesh grafting and Meek micrografting are split-thickness skin graft expansion techniques. This study aimed to compare the effectiveness of Meek and Mesh expansion ratios 1:2 and 1:3 in smaller wounds. An intra-patient randomized controlled trial was conducted at two burn centers (the Netherlands and Belgium). Wound outcomes, e.g., take rate, re-epithelialization rate, and donor site size, were measured. At 3 months post-surgery, patient preference and scar quality were evaluated with the Patient and Observer Scar Assessment Scale (POSAS), cutometer and dermaspectrometer. Seventy patients with a TBSA of 10 ± 10% (mean ± SD) were included. The take rate was 79 ± 25% vs. 87 ± 19% (<i>p</i> = 0.003), Meek vs. Mesh, respectively. At follow-up, a majority of observer and patient POSAS items were statistically significantly lower, corresponding with better scar quality for Mesh grafting compared to Meek micrografting. The scar elasticity was 0.37 ± 0.20 vs. 0.42 ± 0.21 (<i>p</i> = 0.013) and mean melanin 13.3 ± 8.3 vs. 12.1 ± 7.7 (<i>p</i> = 0.019) for Meek vs. Mesh, respectively, and the patient preference was 32%, 49%, and 19% for Meek, Mesh, and no preference. Other outcomes showed no statistically significant difference. In patients with smaller wounds, Mesh showed superiority on most wound and short-term scar results. Nevertheless, patient preference within the 1:3 expansion ratio group and donor site size were in favor of Meek. |
| format | Article |
| id | doaj-art-4c48dff0db5847aab0e61865892aed02 |
| institution | Kabale University |
| issn | 2673-1991 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | European Burn Journal |
| spelling | doaj-art-4c48dff0db5847aab0e61865892aed022025-08-20T03:27:24ZengMDPI AGEuropean Burn Journal2673-19912025-05-01622610.3390/ebj6020026Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled TrialDanielle Rijpma0Karel Claes1Anouk Pijpe2Henk Hoeksema3Ignace De Decker4Jozef Verbelen5Matthea Stoop6Kimberly De Mey7Febe Hoste8Paul van Zuijlen9Stan Monstrey10Annebeth Meij-de Vries11Alliance of Dutch Burn Care, Burn Center Beverwijk, Red Cross Hospital, Vondellaan 13, 1942 LE Beverwijk, The NetherlandsDepartment of Plastic Surgery, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, BelgiumAlliance of Dutch Burn Care, Burn Center Beverwijk, Red Cross Hospital, Vondellaan 13, 1942 LE Beverwijk, The NetherlandsDepartment of Plastic Surgery, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, BelgiumDepartment of Plastic Surgery, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, BelgiumBurn Center, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, BelgiumAlliance of Dutch Burn Care, Burn Center Beverwijk, Red Cross Hospital, Vondellaan 13, 1942 LE Beverwijk, The NetherlandsBurn Center, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, BelgiumFaculty of Medicine and Health Sciences, Ghent University Hospital, 9000 Ghent, BelgiumAlliance of Dutch Burn Care, Burn Center Beverwijk, Red Cross Hospital, Vondellaan 13, 1942 LE Beverwijk, The NetherlandsDepartment of Plastic Surgery, Ghent University Hospital, C. Heymanslaan 10, 9000 Ghent, BelgiumAlliance of Dutch Burn Care, Burn Center Beverwijk, Red Cross Hospital, Vondellaan 13, 1942 LE Beverwijk, The NetherlandsMesh grafting and Meek micrografting are split-thickness skin graft expansion techniques. This study aimed to compare the effectiveness of Meek and Mesh expansion ratios 1:2 and 1:3 in smaller wounds. An intra-patient randomized controlled trial was conducted at two burn centers (the Netherlands and Belgium). Wound outcomes, e.g., take rate, re-epithelialization rate, and donor site size, were measured. At 3 months post-surgery, patient preference and scar quality were evaluated with the Patient and Observer Scar Assessment Scale (POSAS), cutometer and dermaspectrometer. Seventy patients with a TBSA of 10 ± 10% (mean ± SD) were included. The take rate was 79 ± 25% vs. 87 ± 19% (<i>p</i> = 0.003), Meek vs. Mesh, respectively. At follow-up, a majority of observer and patient POSAS items were statistically significantly lower, corresponding with better scar quality for Mesh grafting compared to Meek micrografting. The scar elasticity was 0.37 ± 0.20 vs. 0.42 ± 0.21 (<i>p</i> = 0.013) and mean melanin 13.3 ± 8.3 vs. 12.1 ± 7.7 (<i>p</i> = 0.019) for Meek vs. Mesh, respectively, and the patient preference was 32%, 49%, and 19% for Meek, Mesh, and no preference. Other outcomes showed no statistically significant difference. In patients with smaller wounds, Mesh showed superiority on most wound and short-term scar results. Nevertheless, patient preference within the 1:3 expansion ratio group and donor site size were in favor of Meek.https://www.mdpi.com/2673-1991/6/2/26burn woundsscarsrandomized controlled trialmesh graftingmeek micrografting |
| spellingShingle | Danielle Rijpma Karel Claes Anouk Pijpe Henk Hoeksema Ignace De Decker Jozef Verbelen Matthea Stoop Kimberly De Mey Febe Hoste Paul van Zuijlen Stan Monstrey Annebeth Meij-de Vries Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial European Burn Journal burn wounds scars randomized controlled trial mesh grafting meek micrografting |
| title | Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial |
| title_full | Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial |
| title_fullStr | Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial |
| title_full_unstemmed | Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial |
| title_short | Wound and Short-Term Scar Outcomes of Meek Micrografting Versus Mesh Grafting: An Intra-Patient Randomized Controlled Trial |
| title_sort | wound and short term scar outcomes of meek micrografting versus mesh grafting an intra patient randomized controlled trial |
| topic | burn wounds scars randomized controlled trial mesh grafting meek micrografting |
| url | https://www.mdpi.com/2673-1991/6/2/26 |
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