NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY

Amlodipine combines the most important clinical effects of calcium antagonists with minimal side effects of both its ATC class  and drugs of previous generations. Its high antihypertensive  activity is not in doubt. Proven ability to improve long-term prognosis is a priority when choosing of amlodip...

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Main Authors: A. V. Rudenko, B. A. Rudenko
Format: Article
Language:English
Published: Столичная издательская компания 2015-09-01
Series:Рациональная фармакотерапия в кардиологии
Subjects:
Online Access:https://www.rpcardio.online/jour/article/view/112
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author A. V. Rudenko
B. A. Rudenko
author_facet A. V. Rudenko
B. A. Rudenko
author_sort A. V. Rudenko
collection DOAJ
description Amlodipine combines the most important clinical effects of calcium antagonists with minimal side effects of both its ATC class  and drugs of previous generations. Its high antihypertensive  activity is not in doubt. Proven ability to improve long-term prognosis is a priority when choosing of amlodipine for treatment of hypertensive patients. This is particularly important for the primary prevention in the presence of both risk factors and associated clinical conditions.  Amlodipine therapy significantly reduced cardiovascular events incidence in patients with atherosclerosis, even if they have no arterial hypertension. The likely rationales for this amlodipine effect are its vasoprotective properties, ability to re- duce vascular stiffness and to slow down the progression of atherosclerosis.
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institution Kabale University
issn 1819-6446
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language English
publishDate 2015-09-01
publisher Столичная издательская компания
record_format Article
series Рациональная фармакотерапия в кардиологии
spelling doaj-art-4c472b0cc1e0494da28a6406cb5eb6202025-08-23T10:00:16ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-09-019444845410.20996/1819-6446-2013-9-4-448-454111NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORYA. V. Rudenko0B. A. Rudenko1Russian Cardiology Research and Production Complex, MoscowState Research Center for Preventive Medicin, MoscowAmlodipine combines the most important clinical effects of calcium antagonists with minimal side effects of both its ATC class  and drugs of previous generations. Its high antihypertensive  activity is not in doubt. Proven ability to improve long-term prognosis is a priority when choosing of amlodipine for treatment of hypertensive patients. This is particularly important for the primary prevention in the presence of both risk factors and associated clinical conditions.  Amlodipine therapy significantly reduced cardiovascular events incidence in patients with atherosclerosis, even if they have no arterial hypertension. The likely rationales for this amlodipine effect are its vasoprotective properties, ability to re- duce vascular stiffness and to slow down the progression of atherosclerosis.https://www.rpcardio.online/jour/article/view/112amlodipinearterial hypertensioncardiovascular complications
spellingShingle A. V. Rudenko
B. A. Rudenko
NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY
Рациональная фармакотерапия в кардиологии
amlodipine
arterial hypertension
cardiovascular complications
title NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY
title_full NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY
title_fullStr NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY
title_full_unstemmed NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY
title_short NORVASC® IN RUSSIA 20 YEARS LATER: CONTINUATION OF THE HISTORY
title_sort norvasc r in russia 20 years later continuation of the history
topic amlodipine
arterial hypertension
cardiovascular complications
url https://www.rpcardio.online/jour/article/view/112
work_keys_str_mv AT avrudenko norvascinrussia20yearslatercontinuationofthehistory
AT barudenko norvascinrussia20yearslatercontinuationofthehistory